CDK16 and PJA1

Number of citations of the paper that reports this interaction (PubMedID 21461837)
7

Data Source:
BioGRID (enzymatic study)

		CDK16	PJA1
Description		cyclin dependent kinase 16	praja ring finger ubiquitin ligase 1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Synaptic Vesicle Microtubule Cytoskeleton Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Neuron Projection	Cytoplasm
	Molecular Function	Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Exocytosis Spermatogenesis Growth Hormone Secretion Neuron Projection Development Regulation Of Cell Cycle Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus	Protein Ubiquitination Protein Catabolic Process
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs		(2Z,3E)-2,3'-biindole-2',3(1H,1'H)-dione 3-{O-[(3R)-3,4-dihydroxybutyl]oxime} Fostamatinib
Diseases
GWAS			Birth weight ( 31043758) Body mass index ( 29273807) Platelet count ( 32888494) Plateletcrit ( 32888494) Schizophrenia ( 25056061 29483656)
Interacting Genes		18 interacting genes: APP APPBP2 ATRIP BAG6 CCND3 CDK5 CDK5R1 PJA1 PRKACA S100A10 SEC23A SIRPA YWHAE YWHAG YWHAH YWHAQ YWHAZ ZBTB14	64 interacting genes: ABR ASCC2 ATP5F1C ATXN3 ATXN3L CAMK1G CDK16 COASY CSAG3 DDX54 EED ELAC1 ESPL1 EZH2 FGF12 GATD3 GLO1 GSR GTF2I HNRNPC HNRNPL HOMER2 JOSD1 KIF22 LCP2 LRG1 MAGEB4 MAGED1 MDM2 METAP2 NAGK NATD1 NDN OTUB1 OTUB2 PCCA PFKFB4 PHGDH PIP4K2C RIBC2 SPTBN1 STAC STAM STAMBP SUZ12 TAF9 TK1 TMEM214 TSSK3 TXNDC5 UBE2D2 UBE2D3 UBE2E3 UBE2K UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP8 ZNF440
Entrez ID		5127	64219
HPRD ID		02409	02335
Ensembl ID		ENSG00000102225	ENSG00000181191
Uniprot IDs		A0A024R183 A0A140VK97 Q00536 Q9BRL4	Q8NG27
PDB IDs		3MTL 5G6V	2L0B
Enriched GO Terms of Interacting Partners?
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