HERC5 and ERCC2

  • Number of citations of the paper that reports this interaction (PubMedID 16884686)
  • 36

HERC5

ERCC2

Description HECT and RLD domain containing E3 ubiquitin protein ligase 5 ERCC excision repair 2, TFIIH core complex helicase subunit
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Pulmonary function decline ( 22424883)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Lung Cancer (DNA repair capacity) ( 23108145)
  • Sleep (1/2-day periodicity) ( 33075057)
Interacting Genes 15 interacting genes: BECN1 CCNA2 CCNB1 CCND1 CCNE1 CDKN1A ERCC2 IRF3 MTDH NME2 PITX2 STK38 UBE2D1 UBE2D2 UBE2L6 17 interacting genes: AR CDK1 CDK7 ERCC3 ERCC5 GTF2E1 GTF2H1 GTF2H2 GTF2H2C_2 GTF2H3 HERC5 MNAT1 MTDH RAD51 RAD52 TP53 TRIM25
Entrez ID 51191 2068
HPRD ID 10502 00530
Ensembl ID ENSG00000138646 ENSG00000104884
Uniprot IDs B4DXV3 Q9UII4 P18074
PDB IDs 5IVW 5IY6 5IY7 5IY8 5IY9 5OF4 6NMI 6O9L 6O9M 6RO4 6TUN
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?