ERCC2 and CDK7

  • Number of citations of the paper that reports this interaction (PubMedID 26186194)
  • 524
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, proximity labelling technology, affinity chromatography technology, biochemical, affinity chromatography technology)
  • HPRD (in vitro)

ERCC2

CDK7

Description ERCC excision repair 2, TFIIH core complex helicase subunit cyclin dependent kinase 7
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Lung Cancer (DNA repair capacity) ( 23108145)
  • Sleep (1/2-day periodicity) ( 33075057)
Interacting Genes 17 interacting genes: AR CDK1 CDK7 ERCC3 ERCC5 GTF2E1 GTF2H1 GTF2H2 GTF2H2C_2 GTF2H3 HERC5 MNAT1 MTDH RAD51 RAD52 TP53 TRIM25 45 interacting genes: ADAMTS6 APP AR BRCA1 CCND2 CCNH CDC37 CDK1 CDK2 CDK6 CDK9 CTDP1 CUX1 E2F1 ERCC2 ERCC3 ESR1 GTF2E1 GTF2E2 GTF2H1 GTF2H2 GTF2H3 GTF2H5 H1-1 HLA-DQA1 HSD17B4 LASP1 MBP MCM7 MNAT1 NEK6 PCGF6 POLR2B PRKCI RARA SMAD1 SRPK1 SRPK2 SUPT5H TAF7 TCEA1 THRA TP53 UBE2D1 VDR
Entrez ID 2068 1022
HPRD ID 00530 15993
Ensembl ID ENSG00000104884 ENSG00000134058
Uniprot IDs P18074 A0A0S2Z3F9 D6R9G1 D6RFL0 P50613
PDB IDs 5IVW 5IY6 5IY7 5IY8 5IY9 5OF4 6NMI 6O9L 6O9M 6RO4 6TUN 1LG3 1PA8 1UA2 2HIC 6O9L 6XBZ 6XD3 7B5O 7B5Q
Enriched GO Terms of Interacting Partners?
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