IL22 and IL10RB

Number of citations of the paper that reports this interaction (PubMedID 10875937)
157

Data Source:
HPRD (in vivo)

		IL22	IL10RB
Description		interleukin 22	interleukin 10 receptor subunit beta
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Integral Component Of Membrane Interleukin-28 Receptor Complex
	Molecular Function	Cytokine Activity Protein Binding Interleukin-22 Receptor Binding	Cytokine Receptor Activity Interleukin-10 Receptor Activity Protein Binding Signaling Receptor Activity
	Biological Process	Acute-phase Response Inflammatory Response Signal Transduction Response To Glucocorticoid	Inflammatory Response Immune Response Signal Transduction Cytokine-mediated Signaling Pathway Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Defense Response To Virus Positive Regulation Of Cellular Respiration
Pathways		Interleukin-20 family signaling	Other interleukin signaling Interleukin-10 signaling Interleukin-20 family signaling
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Inflammatory bowel disease ( 23128233) Ulcerative colitis ( 19122664)	Blood protein levels ( 30072576) Crohn's disease ( 23128233) Multiple sclerosis ( 31604244) Narcolepsy ( 24204295 23459209)
Interacting Genes		3 interacting genes: IL10RB IL22RA1 IL22RA2	9 interacting genes: CBR3 IFNL2 IFNL3 IL10 IL10RA IL22 RCAN1 UCN2 UCN3
Entrez ID		50616	3588
HPRD ID		05621	00473
Ensembl ID		ENSG00000127318	ENSG00000243646
Uniprot IDs		Q9GZX6	Q08334
PDB IDs		1M4R 1YKB 3DGC 3DLQ 3G9V 3Q1S	3LQM 5T5W
Enriched GO Terms of Interacting Partners?
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