IL10RB and IL22

Number of citations of the paper that reports this interaction (PubMedID 10875937)
157

Data Source:
HPRD (in vivo)

		IL10RB	IL22
Description		interleukin 10 receptor subunit beta	interleukin 22
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Interleukin-28 Receptor Complex	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Receptor Activity Interleukin-10 Receptor Activity Protein Binding Signaling Receptor Activity	Cytokine Activity Protein Binding Interleukin-22 Receptor Binding
	Biological Process	Inflammatory Response Immune Response Signal Transduction Cytokine-mediated Signaling Pathway Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Defense Response To Virus Positive Regulation Of Cellular Respiration	Acute-phase Response Inflammatory Response Signal Transduction Response To Glucocorticoid
Pathways		Other interleukin signaling Interleukin-10 signaling Interleukin-20 family signaling	Interleukin-20 family signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Crohn's disease ( 23128233) Multiple sclerosis ( 31604244) Narcolepsy ( 24204295 23459209)	Alopecia areata ( 25608926) Inflammatory bowel disease ( 23128233) Ulcerative colitis ( 19122664)
Interacting Genes		9 interacting genes: CBR3 IFNL2 IFNL3 IL10 IL10RA IL22 RCAN1 UCN2 UCN3	3 interacting genes: IL10RB IL22RA1 IL22RA2
Entrez ID		3588	50616
HPRD ID		00473	05621
Ensembl ID		ENSG00000243646	ENSG00000127318
Uniprot IDs		Q08334	Q9GZX6
PDB IDs		3LQM 5T5W	1M4R 1YKB 3DGC 3DLQ 3G9V 3Q1S
Enriched GO Terms of Interacting Partners?
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