IL10RB and IFNL2

Number of citations of the paper that reports this interaction (PubMedID 12469119)
542

Data Source:
HPRD (in vivo)

		IL10RB	IFNL2
Description		interleukin 10 receptor subunit beta	interferon lambda 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Interleukin-28 Receptor Complex	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Receptor Activity Interleukin-10 Receptor Activity Protein Binding Signaling Receptor Activity	Signaling Receptor Binding Cytokine Activity
	Biological Process	Inflammatory Response Immune Response Signal Transduction Cytokine-mediated Signaling Pathway Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Defense Response To Virus Positive Regulation Of Cellular Respiration	Mucosal Immune Response Receptor Signaling Pathway Via JAK-STAT Innate Immune Response Positive Regulation Of Immune Response Defense Response To Virus
Pathways		Other interleukin signaling Interleukin-10 signaling Interleukin-20 family signaling	Interleukin-20 family signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Crohn's disease ( 23128233) Multiple sclerosis ( 31604244) Narcolepsy ( 24204295 23459209)	Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Leukocyte telomere length ( 32109421)
Interacting Genes		9 interacting genes: CBR3 IFNL2 IFNL3 IL10 IL10RA IL22 RCAN1 UCN2 UCN3	2 interacting genes: IFNLR1 IL10RB
Entrez ID		3588	282616
HPRD ID		00473	09586
Ensembl ID		ENSG00000243646	ENSG00000183709
Uniprot IDs		Q08334	Q8IZJ0
PDB IDs		3LQM 5T5W
Enriched GO Terms of Interacting Partners?
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