ATP2A2 and IRS1

  • Number of citations of the paper that reports this interaction (PubMedID 9295312)
  • 15
  • Data Source:
  • HPRD (in vivo, in vitro)

ATP2A2

IRS1

Description ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 insulin receptor substrate 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Glucose homeostasis traits ( 25524916)
  • Protein quantitative trait loci ( 18464913)
  • QT interval ( 24952745 29874175)
  • Schizophrenia ( 28991256 25056061 29483656 30285260)
  • Waist circumference ( 28552196)
Interacting Genes 16 interacting genes: BCL2 CAMK2A CCR4 CHRM5 F2RL1 FGL2 HGS IRS1 IRS2 MDM2 PLN S100A1 SMCO4 SPP1 TRIM14 UNG 81 interacting genes: AKT1 ALK AP3S1 APP ATP2A1 ATP2A2 ATP2A3 BCL2L1 BCR CAV1 CDH1 CHUK CRK CSNK2A1 CSNK2B EGFR ERBB2 FBXO25 FBXW8 FER FES FYN GHR GRB10 GRB14 GRB2 IGF1R IKBKB IL4R INSR JAK1 JAK2 JAK3 MAPK1 MAPK3 MAPK8 MAPK9 MTOR NCK2 NEDD4 NPM1 NRDC NTRK1 NUMB PASK PDPK1 PELI1 PHIP PIK3R1 PIK3R2 PIK3R3 PLCG2 PRKCD PRKCG PRKCQ PRKCZ PTK2 PTPN1 PTPN11 PTPRC PTPRD PTPRF PTPRU RAD51 ROCK1 RPS6KB1 RPTOR SHC1 SIK2 SOCS1 SOCS3 TERT TRIM72 TUB TYK2 UBC UBTF YWHAB YWHAE YWHAG YWHAZ
Entrez ID 488 3667
HPRD ID 00161 00943
Ensembl ID ENSG00000174437 ENSG00000169047
Uniprot IDs A0A0S2Z3L2 P16615 P35568
PDB IDs 5ZTF 6JJU 6LLE 6LLY 6LN5 6LN6 6LN7 6LN8 6LN9 7BT2 1IRS 1K3A 1QQG 2Z8C 5U1M 6BNT
Enriched GO Terms of Interacting Partners?
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