ATP2A2 and FGL2

		ATP2A2	FGL2
Description		ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2	fibrinogen like 2
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Vesicle Membrane Membrane Integral Component Of Membrane Sarcoplasmic Reticulum Platelet Dense Tubular Network Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Protein-containing Complex Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm Apical Ectoplasmic Specialization Ribbon Synapse Plasma Membrane Bounded Cell Projection	Extracellular Region Fibrinogen Complex Extracellular Space Collagen-containing Extracellular Matrix Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	P-type Calcium Transporter Activity Calcium Ion Binding Protein Binding ATP Binding P-type Ion Transporter Activity ATP Hydrolysis Activity Enzyme Binding Lutropin-choriogonadotropic Hormone Receptor Binding Transmembrane Transporter Binding S100 Protein Binding P-type Calcium Transporter Activity Involved In Regulation Of Cardiac Muscle Cell Membrane Potential	Signaling Receptor Binding Extracellular Matrix Structural Constituent Peptidase Activity
	Biological Process	Autophagosome Assembly Regulation Of The Force Of Heart Contraction Skeletal Muscle Contraction Cellular Calcium Ion Homeostasis ER-nucleus Signaling Pathway Cell Adhesion Epidermis Development Positive Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Transition Between Fast And Slow Fiber Cardiac Muscle Hypertrophy In Response To Stress Autophagosome Membrane Docking Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Response To Lipopolysaccharide T-tubule Organization Ion Transmembrane Transport Cellular Response To Oxidative Stress Cellular Response To Heat Response To Endoplasmic Reticulum Stress Negative Regulation Of Heart Contraction Relaxation Of Cardiac Muscle Sarcoplasmic Reticulum Calcium Ion Transport Calcium Ion Transmembrane Transport Regulation Of Cardiac Muscle Cell Membrane Potential Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Organelle Localization By Membrane Tethering Negative Regulation Of Receptor Binding Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Calcium Ion Transport From Cytosol To Endoplasmic Reticulum Regulation Of Cardiac Conduction Calcium Ion Import Into Sarcoplasmic Reticulum Mitochondrion-endoplasmic Reticulum Membrane Tethering	T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Negative Regulation Of Dendritic Cell Antigen Processing And Presentation Negative Regulation Of Macrophage Antigen Processing And Presentation Proteolysis Negative Regulation Of Memory T Cell Differentiation Negative Regulation Of Defense Response To Virus
Pathways		Pre-NOTCH Processing in Golgi Reduction of cytosolic Ca++ levels Ion homeostasis Ion transport by P-type ATPases	Neutrophil degranulation
Drugs		Desflurane Istaroxime
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Glucose homeostasis traits ( 25524916) Protein quantitative trait loci ( 18464913) QT interval ( 24952745 29874175) Schizophrenia ( 28991256 25056061 29483656 30285260) Waist circumference ( 28552196)	Crohn's disease ( 30500874)
Interacting Genes		16 interacting genes: BCL2 CAMK2A CCR4 CHRM5 F2RL1 FGL2 HGS IRS1 IRS2 MDM2 PLN S100A1 SMCO4 SPP1 TRIM14 UNG	1 interacting genes: ATP2A2
Entrez ID		488	10875
HPRD ID		00161	16098
Ensembl ID		ENSG00000174437	ENSG00000127951
Uniprot IDs		A0A0S2Z3L2 P16615	A4D1B8 Q14314
PDB IDs		5ZTF 6JJU 6LLE 6LLY 6LN5 6LN6 6LN7 6LN8 6LN9 7BT2
Enriched GO Terms of Interacting Partners?
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