IRS1 and PIK3R2

  • Number of citations of the paper that reports this interaction (PubMedID 12730242)
  • 22
  • Data Source:
  • HPRD (in vivo, two hybrid)

IRS1

PIK3R2

Description insulin receptor substrate 1 phosphoinositide-3-kinase regulatory subunit 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Basophil count ( 32888494)
  • Basophil percentage of white cells ( 32888494)
  • Mental health study participation (completed survey) ( 31263887)
Interacting Genes 81 interacting genes: AKT1 ALK AP3S1 APP ATP2A1 ATP2A2 ATP2A3 BCL2L1 BCR CAV1 CDH1 CHUK CRK CSNK2A1 CSNK2B EGFR ERBB2 FBXO25 FBXW8 FER FES FYN GHR GRB10 GRB14 GRB2 IGF1R IKBKB IL4R INSR JAK1 JAK2 JAK3 MAPK1 MAPK3 MAPK8 MAPK9 MTOR NCK2 NEDD4 NPM1 NRDC NTRK1 NUMB PASK PDPK1 PELI1 PHIP PIK3R1 PIK3R2 PIK3R3 PLCG2 PRKCD PRKCG PRKCQ PRKCZ PTK2 PTPN1 PTPN11 PTPRC PTPRD PTPRF PTPRU RAD51 ROCK1 RPS6KB1 RPTOR SHC1 SIK2 SOCS1 SOCS3 TERT TRIM72 TUB TYK2 UBC UBTF YWHAB YWHAE YWHAG YWHAZ 59 interacting genes: APP APPL1 AR ARRB1 AXL CBL CD28 CRK CRKL CSF1R DYDC1 EGF EGFR ENKUR EPHA2 ERBB2 ERBB3 ERBB4 FBXL2 FGFR1 FYN GAB1 GHR GOLGA2 GRB2 GRN HCK IGF1R IKZF3 IRS1 IRS2 KIT KRAS KRT15 KRT20 KRT38 LAMB2 LMNA LTBP3 MET MRFAP1L1 PDGFRB PIK3CD RINT1 SEPTIN2 SHC1 SOCS1 SOCS6 SOCS7 SOS1 STAB1 STAT3 SYK TEC TGFBR1 TGFBR2 TRIM23 WASF3 YWHAB
Entrez ID 3667 5296
HPRD ID 00943 04404
Ensembl ID ENSG00000169047 ENSG00000105647
Uniprot IDs P35568 O00459
PDB IDs 1IRS 1K3A 1QQG 2Z8C 5U1M 6BNT 2KT1 2XS6 3MTT 3O5Z 6OX7 6U28
Enriched GO Terms of Interacting Partners?
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