FLNC and CAPN3

  • Number of citations of the paper that reports this interaction (PubMedID 14506720)
  • 27
  • Data Source:
  • BioGRID (enzymatic study)
  • HPRD (in vitro, in vivo)

FLNC

CAPN3

Description filamin C calpain 3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Dilated cardiomyopathy ( 33495596)
  • Dilated cardiomyopathy (MTAG) ( 33495596)
  • Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597)
  • Reading disability or specific language impairment (pleiotropy) ( 25065397)
  • Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)
  • Fibrinogen levels ( 28107422 26561523)
  • Granulocyte percentage of myeloid white cells ( 27863252)
  • HDL cholesterol levels ( 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Metabolite levels ( 23823483)
  • Monocyte count ( 32888494 27863252)
  • Monocyte percentage of white cells ( 32888494 27863252)
  • Triglyceride levels ( 32203549 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
  • Triglycerides ( 24097068 25961943 20686565)
Interacting Genes 35 interacting genes: ADRA1A ADRA1B ADRA1D CAPN3 CDC42 ENO1 FURIN HIPK3 HSPB2 INPPL1 KCND2 KY MAP2K4 MTDH MYBPC2 MYOT MYOZ1 MYOZ2 MYOZ3 NPHP1 PHLDB2 PRKAB2 PRKCA REPS1 RPS6KA2 SGCD SGCG SYNPO2 TRIM54 TRIM55 TRIM63 USP25 WNK1 XIRP1 XIRP2 32 interacting genes: AMOT C1QTNF9 CCDC102B CEP76 CMYA5 CRYAB DYSF EXOC8 FLNC FNDC3B FXR1 GTPBP3 KANK2 MAP1LC3C MMP2 MYBPC1 MYBPH NECAB2 NTAQ1 OSGIN1 POMP PREPL PSMC3 PSMD1 RNF167 RUFY3 TFCP2 TRIM55 TRIM63 TTN UBE3A YWHAQ
Entrez ID 2318 825
HPRD ID 00018 00255
Ensembl ID ENSG00000128591 ENSG00000092529
Uniprot IDs Q14315 Q59H94 A0A0S2Z3E1 P20807
PDB IDs 1V05 2D7M 2D7N 2D7O 2D7P 2D7Q 2K9U 2NQC 3V8O 4MGX 1Y9V 4OKH 6BDT 6BGP 6BJD 6BKJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?