FLNC and MAP2K4

  • Number of citations of the paper that reports this interaction (PubMedID 9006895)
  • 35
  • Data Source:
  • HPRD (in vitro, in vivo, two hybrid)

FLNC

MAP2K4

Description filamin C mitogen-activated protein kinase kinase 4
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Dilated cardiomyopathy ( 33495596)
  • Dilated cardiomyopathy (MTAG) ( 33495596)
  • Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597)
  • Reading disability or specific language impairment (pleiotropy) ( 25065397)
  • Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)
  • Asthma ( 32296059)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Estimated glomerular filtration rate ( 31152163)
  • Response to amphetamines ( 22952603)
  • Serum alkaline phosphatase levels ( 33339817)
Interacting Genes 35 interacting genes: ADRA1A ADRA1B ADRA1D CAPN3 CDC42 ENO1 FURIN HIPK3 HSPB2 INPPL1 KCND2 KY MAP2K4 MTDH MYBPC2 MYOT MYOZ1 MYOZ2 MYOZ3 NPHP1 PHLDB2 PRKAB2 PRKCA REPS1 RPS6KA2 SGCD SGCG SYNPO2 TRIM54 TRIM55 TRIM63 USP25 WNK1 XIRP1 XIRP2 44 interacting genes: AKT1 ALDOB APP ARRB1 ARRB2 CFLAR CYLC2 DUSP22 EFNA4 FBP2 FLNA FLNC GEMIN5 ITCH JUN LRRK2 MAP2K6 MAP3K1 MAP3K10 MAP3K11 MAP3K12 MAP3K14 MAP3K2 MAP3K20 MAP3K3 MAP3K4 MAP3K5 MAP3K7 MAP3K8 MAP4K2 MAPK1 MAPK10 MAPK12 MAPK14 MAPK7 MAPK8 MAPK8IP3 MAPK9 NBR1 RBBP8 SPAG9 STX17 TRIB1 UBC
Entrez ID 2318 6416
HPRD ID 00018 03213
Ensembl ID ENSG00000128591 ENSG00000065559
Uniprot IDs Q14315 Q59H94 P45985
PDB IDs 1V05 2D7M 2D7N 2D7O 2D7P 2D7Q 2K9U 2NQC 3V8O 4MGX 3ALN 3ALO 3VUT
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?