NBN and XRCC4

  • Number of citations of the paper that reports this interaction (PubMedID 18458108)
  • 25
  • Data Source:
  • BioGRID (two hybrid)

NBN

XRCC4

Description nibrin X-ray repair cross complementing 4
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Lymphocyte counts ( 32888494)
  • Lymphocyte percentage of white cells ( 32888494)
  • Clozapine-induced agranulocytosis ( 25187353)
  • Diisocyanate-induced asthma ( 25918132)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Heel bone mineral density ( 30598549)
  • Osteoarthritis biomarkers ( 25057126)
  • Squamous cell lung carcinoma ( 28604730)
  • Type 2 diabetes ( 25760438)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • White matter integrity (fractional anisotropy) ( 29752348)
  • White matter integrity (mean diffusivity) ( 29752348)
Interacting Genes 35 interacting genes: ATF2 ATM ATR BAP1 BRCA1 CASC3 CCNE1 CDK9 CHEK2 DCLRE1C EP300 FANCD2 H2AX H3-4 HIF1A MDC1 MRE11 NAT2 NCL PRKDC RAD18 RAD50 RAD51 RECQL5 SIRT1 SNAI1 SUMO2 TERF1 TLK1 TREX1 UBE2D1 UBE2N VRK1 XRCC4 XRCC5 24 interacting genes: ACTN1 AHNAK APLF APTX ASTE1 BIN1 CAAP1 CALM1 CHD3 CSNK2A1 FAM9B GSC2 GZMB HAUS2 IFFO1 KRT27 LIG4 MAGEA6 NBN NHEJ1 OGT PNKP PRKDC VIM
Entrez ID 4683 7518
HPRD ID 04050 15951
Ensembl ID ENSG00000104320 ENSG00000152422
Uniprot IDs A0A0C4DG07 O60934 A0A024RAL0 A0A024RAP0 A0A024RAQ8 Q13426 Q7Z763
PDB IDs 5WQD 1FU1 1IK9 3II6 3MUD 3Q4F 3RWR 3SR2 3W03 4XA4 5CHX 5CJ0 5CJ4 5E50 5WJ7 5WLZ 6ABO
Enriched GO Terms of Interacting Partners?
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