XRCC4 and APLF

  • Number of citations of the paper that reports this interaction (PubMedID 17396150)
  • 68
  • Data Source:
  • HPRD (in vitro)

XRCC4

APLF

Description X-ray repair cross complementing 4 aprataxin and PNKP like factor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Clozapine-induced agranulocytosis ( 25187353)
  • Diisocyanate-induced asthma ( 25918132)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Heel bone mineral density ( 30598549)
  • Osteoarthritis biomarkers ( 25057126)
  • Squamous cell lung carcinoma ( 28604730)
  • Type 2 diabetes ( 25760438)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • White matter integrity (fractional anisotropy) ( 29752348)
  • White matter integrity (mean diffusivity) ( 29752348)
  • Restless legs syndrome ( 29029846)
  • Urate levels in lean individuals ( 25811787)
Interacting Genes 24 interacting genes: ACTN1 AHNAK APLF APTX ASTE1 BIN1 CAAP1 CALM1 CHD3 CSNK2A1 FAM9B GSC2 GZMB HAUS2 IFFO1 KRT27 LIG4 MAGEA6 NBN NHEJ1 OGT PNKP PRKDC VIM 7 interacting genes: APP FBXO25 GMCL1 IRX5 LIG4 XRCC1 XRCC4
Entrez ID 7518 200558
HPRD ID 15951 09848
Ensembl ID ENSG00000152422 ENSG00000169621
Uniprot IDs A0A024RAL0 A0A024RAP0 A0A024RAQ8 Q13426 Q7Z763 Q8IW19
PDB IDs 1FU1 1IK9 3II6 3MUD 3Q4F 3RWR 3SR2 3W03 4XA4 5CHX 5CJ0 5CJ4 5E50 5WJ7 5WLZ 6ABO 2KQB 2KQC 2KQD 2KQE 2KUO 5E50 5W7W 5W7X 5W7Y 6ERF 6TYT 6TYW 6TYZ
Enriched GO Terms of Interacting Partners?
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