MYL6 and MOB4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MYL6	MOB4
Description		myosin light chain 6	MOB family member 4, phocein
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Brush Border Membrane Myosin Complex Unconventional Myosin Complex Vesicle Extracellular Exosome	Cytoplasm Golgi Apparatus Golgi Cisterna Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Microfilament Motor Activity Cytoskeletal Motor Activity Calcium Ion Binding Protein Binding Structural Constituent Of Muscle	Protein Binding Metal Ion Binding
	Biological Process	Muscle Contraction Skeletal Muscle Tissue Development Muscle Filament Sliding
Pathways		EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse Smooth Muscle Contraction RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs
Drugs
Diseases
GWAS		Asthma ( 31619474)	Allergic rhinitis ( 31361310) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Schizophrenia ( 29483656) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		10 interacting genes: ADAMTS12 CYP27B1 DNAJB9 EWSR1 GLP1R GSK3B HMGB2 MLH1 MOB4 NUDT21	33 interacting genes: ARHGEF15 CCDC85B CRMP1 DNM1 EGFR EGLN2 ELK1 EPS15 FADD FBLN1 GDF9 HSPD1 KIDINS220 LATS1 LATS2 LRIF1 MCM2 MED10 MED31 MYL6 MYO9B NME2 PAICS PLEKHM1 PPIL3 PTPRS RAPGEF2 SCMH1 SETDB1 STK11 STK3 THAP4 UBE2V2
Entrez ID		4637	25843
HPRD ID		17618	10165
Ensembl ID		ENSG00000092841	ENSG00000115540
Uniprot IDs		P60660	A0A024R3X9 Q9Y3A3
PDB IDs			5YF4
Enriched GO Terms of Interacting Partners?
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