MSRA and SDHB

Number of citations of the paper that reports this interaction (PubMedID 32456285)
1

Data Source:
BioGRID (two hybrid)

		MSRA	SDHB
Description		methionine sulfoxide reductase A	succinate dehydrogenase complex iron sulfur subunit B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Cytosol Plasma Membrane Actin Cytoskeleton Extracellular Exosome	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex II, Succinate Dehydrogenase Complex (ubiquinone) Plasma Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Peptide-methionine (S)-S-oxide Reductase Activity L-methionine-(S)-S-oxide Reductase Activity	Protein Binding Succinate Dehydrogenase (ubiquinone) Activity Electron Transfer Activity Metal Ion Binding Ubiquinone Binding 2 Iron, 2 Sulfur Cluster Binding 3 Iron, 4 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Cellular Protein Modification Process Methionine Metabolic Process Response To Oxidative Stress Protein Repair Cellular Response To Oxidative Stress	Tricarboxylic Acid Cycle Succinate Metabolic Process Aerobic Respiration Respiratory Electron Transport Chain
Pathways		Protein repair	Respiratory electron transport Citric acid cycle (TCA cycle)
Drugs		1,4-Dithiothreitol	2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol Ubiquinone Q1
Diseases
GWAS		Adiposity ( 19557161) Adult body size ( 32376654) Age at first sexual intercourse ( 27089180) Alzheimer's disease ( 20452100) Asthma-chronic obstructive pulmonary disease overlap syndrome ( 30657218) Autoimmune thyroid disease ( 32581359) Barrett's esophagus ( 27527254) Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Bipolar disorder ( 31043756) Bipolar disorder and schizophrenia ( 22688191) BMI x environmental factors (excluding physical activity) interaction ( 33654129) Body mass index ( 30108283 31453325) Body mass index variance ( 31453325) Body shape index ( 34021172) Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) Bulimia nervosa ( 23568457) Chronotype ( 26835600) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cooked vegetable consumption ( 32066663) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Depression ( 33859377) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Estimated glomerular filtration rate ( 31152163) Feeling worry ( 29500382) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) General factor of neuroticism ( 30867560) General risk tolerance (MTAG) ( 30643258) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) HDL cholesterol levels ( 32203549) Hypertension ( 19430479) Insomnia ( 32332799) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Irritable mood ( 29500382) Joint mobility (Beighton score) ( 27182965) Liver enzyme levels (alanine transaminase) ( 33972514) Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (diuretics) ( 31015401) Medication use (thyroid preparations) ( 31015401) Myopia (pathological) ( 23049088) Neurociticism ( 29500382) Nose size ( 27182965) Obesity (early onset extreme) ( 20421936) Oily fish consumption ( 32066663) Plasma kynurenine to tryptophan ratio in major depressive disorder ( 29317604) Pork consumption ( 32066663) Processed meat consumption ( 32066663) Pulse pressure ( 30578418) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Raw vegetable consumption ( 32066663) Refractive error ( 32231278) Remission after SSRI treatment in MDD or neuroticism ( 29559929) Response to chemotherapy in breast cancer hypertensive cases (cumulative dose) (bevacizumab) ( 25117820) Response to selenium supplementation (change in plasma selenium concentration) ( 33382417) Schizophrenia ( 28991256 21679298 30285260 26198764) Serum metabolite levels ( 33031748) Smoking initiation (ever regular vs never regular) ( 30679032) Systemic lupus erythematosus ( 28714469) Systolic blood pressure ( 30224653 30578418) Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) TPE interval (resting) ( 32386560) Triglyceride levels ( 32203549) Type 2 diabetes ( 30297969) Waist circumference ( 30108283) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Weight ( 30108283)	Body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Height ( 20189936) Hip circumference adjusted for BMI ( 34021172) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		14 interacting genes: ARID2 CCNI COPB2 COPS5 CTNNA3 EFCAB11 FARSB FBXL3 HPCAL4 HSPA4L P4HA3 SDHB SELENBP1 WDR44	16 interacting genes: ABCA1 CA6 CARTPT FLOT1 GEM MFAP2 MSRA PIK3R5 RAP1GAP RPL11 SLC45A1 SLC9A1 SPRY2 STMN1 TARBP1 XRN1
Entrez ID		4482	6390
HPRD ID		03152	01707
Ensembl ID		ENSG00000175806	ENSG00000117118
Uniprot IDs		Q9UJ68	P21912
PDB IDs
Enriched GO Terms of Interacting Partners?
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