SDHB and CA6

		SDHB	CA6
Description		succinate dehydrogenase complex iron sulfur subunit B	carbonic anhydrase 6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex II, Succinate Dehydrogenase Complex (ubiquinone) Plasma Membrane Mitochondrial Membrane	Extracellular Region Extracellular Space Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Succinate Dehydrogenase (ubiquinone) Activity Electron Transfer Activity Metal Ion Binding Ubiquinone Binding 2 Iron, 2 Sulfur Cluster Binding 3 Iron, 4 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding	Carbonate Dehydratase Activity Zinc Ion Binding Hydro-lyase Activity
	Biological Process	Tricarboxylic Acid Cycle Succinate Metabolic Process Aerobic Respiration Respiratory Electron Transport Chain	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste One-carbon Metabolic Process
Pathways		Respiratory electron transport Citric acid cycle (TCA cycle)	Reversible hydration of carbon dioxide
Drugs		2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol Ubiquinone Q1	Benzthiazide Cyclothiazide Zonisamide Mafenide Ellagic acid
Diseases
GWAS		Body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Height ( 20189936) Hip circumference adjusted for BMI ( 34021172) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for body mass index ( 34021172)	Blood protein levels ( 30072576 29875488 28240269) Post bronchodilator FEV1 ( 26634245)
Interacting Genes		16 interacting genes: ABCA1 CA6 CARTPT FLOT1 GEM MFAP2 MSRA PIK3R5 RAP1GAP RPL11 SLC45A1 SLC9A1 SPRY2 STMN1 TARBP1 XRN1	7 interacting genes: FCGRT KRT31 KRT40 MTOR NOTCH2NLA SDHB SLC45A1
Entrez ID		6390	765
HPRD ID		01707	00264
Ensembl ID		ENSG00000117118	ENSG00000131686
Uniprot IDs		P21912	B4DUH8 P23280
PDB IDs			3FE4
Enriched GO Terms of Interacting Partners?
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