MSRA and COPS5

  • Number of citations of the paper that reports this interaction (PubMedID 32456285)
  • 1
  • Data Source:
  • BioGRID (two hybrid)

MSRA

COPS5

Description methionine sulfoxide reductase A COP9 signalosome subunit 5
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adiposity ( 19557161)
  • Adult body size ( 32376654)
  • Age at first sexual intercourse ( 27089180)
  • Alzheimer's disease ( 20452100)
  • Asthma-chronic obstructive pulmonary disease overlap syndrome ( 30657218)
  • Autoimmune thyroid disease ( 32581359)
  • Barrett's esophagus ( 27527254)
  • Barrett's esophagus or Esophageal adenocarcinoma ( 27527254)
  • Bipolar disorder ( 31043756)
  • Bipolar disorder and schizophrenia ( 22688191)
  • BMI x environmental factors (excluding physical activity) interaction ( 33654129)
  • Body mass index ( 30108283 31453325)
  • Body mass index variance ( 31453325)
  • Body shape index ( 34021172)
  • Body size at age 10 ( 32376654)
  • Brain morphology (MOSTest) ( 32665545)
  • Bulimia nervosa ( 23568457)
  • Chronotype ( 26835600)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Cooked vegetable consumption ( 32066663)
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
  • Depression ( 33859377)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Eosinophil percentage of white cells ( 27863252)
  • Estimated glomerular filtration rate ( 31152163)
  • Feeling worry ( 29500382)
  • Fish- and plant-related diet ( 32066663)
  • Fruit consumption ( 32066663)
  • General factor of neuroticism ( 30867560)
  • General risk tolerance (MTAG) ( 30643258)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)
  • HDL cholesterol levels ( 32203549)
  • Hypertension ( 19430479)
  • Insomnia ( 32332799)
  • Insomnia symptoms (never/rarely vs. usually) ( 30804566)
  • Irritable mood ( 29500382)
  • Joint mobility (Beighton score) ( 27182965)
  • Liver enzyme levels (alanine transaminase) ( 33972514)
  • Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (diuretics) ( 31015401)
  • Medication use (thyroid preparations) ( 31015401)
  • Myopia (pathological) ( 23049088)
  • Neurociticism ( 29500382)
  • Nose size ( 27182965)
  • Obesity (early onset extreme) ( 20421936)
  • Oily fish consumption ( 32066663)
  • Plasma kynurenine to tryptophan ratio in major depressive disorder ( 29317604)
  • Pork consumption ( 32066663)
  • Processed meat consumption ( 32066663)
  • Pulse pressure ( 30578418)
  • Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Raw vegetable consumption ( 32066663)
  • Refractive error ( 32231278)
  • Remission after SSRI treatment in MDD or neuroticism ( 29559929)
  • Response to chemotherapy in breast cancer hypertensive cases (cumulative dose) (bevacizumab) ( 25117820)
  • Response to selenium supplementation (change in plasma selenium concentration) ( 33382417)
  • Schizophrenia ( 28991256 21679298 30285260 26198764)
  • Serum metabolite levels ( 33031748)
  • Smoking initiation (ever regular vs never regular) ( 30679032)
  • Systemic lupus erythematosus ( 28714469)
  • Systolic blood pressure ( 30224653 30578418)
  • Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • TPE interval (resting) ( 32386560)
  • Triglyceride levels ( 32203549)
  • Type 2 diabetes ( 30297969)
  • Waist circumference ( 30108283)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
  • Weight ( 30108283)
Interacting Genes 14 interacting genes: ARID2 CCNI COPB2 COPS5 CTNNA3 EFCAB11 FARSB FBXL3 HPCAL4 HSPA4L P4HA3 SDHB SELENBP1 WDR44 99 interacting genes: APCS ARFGAP1 ATM ATRN BCL2L14 BCL3 BRD4 BRSK2 CACNA1C CD274 CD93 CDKN1B CENPT COPS2 COPS3 COPS4 COPS6 COPS7A COPS7B COPS8 COPS9 CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 DDB1 DDO ERN1 ERRFI1 ESR1 F2RL1 GFER GFI1B GPS1 GTPBP3 HAND2 HIF1A HNF4A HNF4G HTR6 IKBKB ITGB2 JUN JUND LASP1 MAP2K2 MAP3K11 MAP3K3 MAP3K7 MAP4K3 MAP4K5 MAPK14 MAPRE1 MAX MDC1 MDM2 MEF2C MEF2D MIF MSRA MTRES1 MYG1 NCOA1 NEDD8 NFKB1 NR4A2 NR4A3 OPRM1 PEA15 PGR PLAC8 PPARG PPOX PPP1CC PRDX2 PRKD1 PTGS2 RAD1 RAD9A RNF139 RORA S100A7 SHANK3 SHISA5 SMAD2 SMAD4 SMAD5 SPP1 SREBF2 TOP2A TP53 TXN TYK2 UCHL1 VTN WNK1 YWHAG
Entrez ID 4482 10987
HPRD ID 03152 06888
Ensembl ID ENSG00000175806 ENSG00000121022
Uniprot IDs Q9UJ68 A0A024R7W9 Q92905
PDB IDs 4D10 4D18 4F7O 4WSN 5JOG 5JOH 5M5Q 6R6H 6R7F 6R7H 6R7I
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?