MIP and KCNJ6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MIP	KCNJ6
Description		major intrinsic protein of lens fiber	potassium inwardly rectifying channel subfamily J member 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Gap Junction Integral Component Of Membrane Apical Plasma Membrane	Golgi Apparatus Plasma Membrane Voltage-gated Potassium Channel Complex
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Calmodulin Binding Water Channel Activity	Inward Rectifier Potassium Channel Activity Protein Binding G-protein Activated Inward Rectifier Potassium Channel Activity
	Biological Process	Water Transport Visual Perception Positive Regulation Of Cell Adhesion Response To Stimulus Protein Homotetramerization Transmembrane Transport Gap Junction-mediated Intercellular Transport	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		Passive transport by Aquaporins	Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs		B-nonylglucoside	Ethanol Halothane Ifenprodil Isavuconazole
Diseases
GWAS		Apolipoprotein A1 levels ( 33730874) Axial length ( 24144296) Serum metabolite levels ( 33031748)	Body size at age 10 ( 32376654) Clostridioides difficle infection ( 33841421) Electroencephalographic traits in alcoholism ( 22554406) Response to placebo treatment in childhood asthma (FVC change) ( 31557306) Rosacea symptom severity ( 29771307)
Interacting Genes		47 interacting genes: AQP9 ATP6V0B CALM1 CD40 CISD2 CLDN5 CRYAA CRYAB CRYBB2 CRYGC ERGIC3 ERVFRD-1 FAM209A FCGR2A FOXA2 GJA3 GJA8 GJB5 GOLM1 GPX8 KCNJ6 LHFPL5 LMNA LRRC4C MFF MGST3 MRM3 MRPS18B MUC1 PDZK1IP1 PRKACA RELL2 SAR1A SGPL1 SLC14A1 SLC18A1 SSMEM1 STX1A STX2 SYAP1 SYT1 SYT2 TMEM139 TMEM154 TMEM52B TMX2 ZFPL1	64 interacting genes: ADRB2 AIG1 APOD BCL2L2 BET1 BIRC5 C14orf180 CMTM5 CNPY3 COL4A5 DLG1 DRD2 EDDM3B ERG28 FAM20B FIS1 FUNDC2 FXYD6 GABBR1 HMOX2 ICMT ITGAM KCNJ3 KCNJ9 LEPROTL1 LPAR3 LPCAT2 MIP MYO15B NINJ2 ORMDL2 PEX11G PEX16 PLLP PMP22 PNLIPRP1 RPRM RPS6KA2 RTP2 SCAMP4 SCARF1 SCD SERTM1 STATH STRIT1 SYT3 THSD7B TM6SF2 TMEM107 TMEM120B TMEM203 TMEM208 TMEM218 TMPPE TNFRSF10C TSPO2 UBIAD1 UNC50 UPK1B VSTM1 XIAP YIPF1 YIPF6 ZDHHC24
Entrez ID		4284	3763
HPRD ID		01098	02929
Ensembl ID		ENSG00000135517	ENSG00000157542
Uniprot IDs		P30301	P48051
PDB IDs
Enriched GO Terms of Interacting Partners?
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