MAP3K3 and MARK2

  • Number of citations of the paper that reports this interaction (PubMedID 14743216)
  • 321
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro)

MAP3K3

MARK2

Description mitogen-activated protein kinase kinase kinase 3 microtubule affinity regulating kinase 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Response to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure) ( 21130132)
Interacting Genes 42 interacting genes: BIRC2 BRCA1 CDC37 COPS5 EGFR GAB1 GLRX3 GTF2I HSP90AA1 HSP90AB1 HSPA2 IKBKB MAP2K3 MAP2K4 MAP2K5 MAP2K7 MAP3K5 MAP3K7 MARK2 MBP NEDD4 NEDD4L NFKBIA PFDN2 PRKACA RCAN1 RIPK1 SMURF1 SPAG9 TOM1L1 TRAF6 TRAF7 VWF WNK1 XIAP YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ ZBTB16 42 interacting genes: BAIAP2 CAMK1 CASK DVL3 FBXO7 FLRT1 GAB1 GSK3B HDAC7 INCENP ISOC1 KIF13B KIFAP3 MAP3K3 MAPT MTCL1 NEDD4 NEDD4L NUAK1 NXF1 OSBP PARD3B PARD6A PINK1 PKD1 PLAAT3 PPP2R5B PRKCE PTPRD RAB11FIP2 RNF41 RPA2 RPS6KB1 SCGB1A1 SMURF1 STK11 STK3 STK4 UTRN YWHAB YWHAQ YWHAZ
Entrez ID 4215 2011
HPRD ID 03965 02753
Ensembl ID ENSG00000198909 ENSG00000072518
Uniprot IDs J3KRN4 Q96HN9 Q99759 A0A140VJP1 A8K2S4 E7ETY4 Q7KZI7
PDB IDs 2C60 2JRH 2O2V 2PPH 4Y5O 4YL6 3IEC 5EAK 5KZ7 5KZ8
Enriched GO Terms of Interacting Partners?
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