MARK2 and PKD1

  • Number of citations of the paper that reports this interaction (PubMedID 19011111)
  • 31
  • Data Source:
  • BioGRID (enzymatic study)

MARK2

PKD1

Description microtubule affinity regulating kinase 2 polycystin 1, transient receptor potential channel interacting
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Response to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure) ( 21130132)
  • Appendicular lean mass ( 33097823)
  • Dilated cardiomyopathy ( 33677556)
  • Estimated glomerular filtration rate ( 31451708)
  • Estimated glomerular filtration rate in non-diabetics ( 31451708)
  • Heel bone mineral density ( 30598549)
  • Height ( 28552196)
  • High light scatter reticulocyte count ( 32888494)
  • Hypertrophic cardiomyopathy (MTAG) ( 33495596)
  • Low hand grip strength (60 years and older) (EWGSOP) ( 33510174)
  • Major depressive disorder ( 29317602)
  • Neutrophil count ( 32888494)
  • Systolic blood pressure ( 30578418)
  • Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes 42 interacting genes: BAIAP2 CAMK1 CASK DVL3 FBXO7 FLRT1 GAB1 GSK3B HDAC7 INCENP ISOC1 KIF13B KIFAP3 MAP3K3 MAPT MTCL1 NEDD4 NEDD4L NUAK1 NXF1 OSBP PARD3B PARD6A PINK1 PKD1 PLAAT3 PPP2R5B PRKCE PTPRD RAB11FIP2 RNF41 RPA2 RPS6KB1 SCGB1A1 SMURF1 STK11 STK3 STK4 UTRN YWHAB YWHAQ YWHAZ 39 interacting genes: ACTN1 ATF7IP BCAR1 CDH1 COL1A1 COL2A1 CTNNA1 CTNNB1 DDX58 DES FN1 HDAC9 JAK2 JUP KRT18 KRT8 LTB4R2 MARK2 NADSYN1 NCF1 NCK2 NTHL1 NTN3 OR1F1 PDPK1 PIP5K1C PKD2 PPL PTK2 PTPRG PXN RGS7 RPL3L SIAH1 SOX17 SRC TLN1 VCL VIM
Entrez ID 2011 5310
HPRD ID 02753 03203
Ensembl ID ENSG00000072518 ENSG00000008710
Uniprot IDs A0A140VJP1 A8K2S4 E7ETY4 Q7KZI7 P98161
PDB IDs 3IEC 5EAK 5KZ7 5KZ8 1B4R 6A70
Enriched GO Terms of Interacting Partners?
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