MCC and GTF2E2

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 87
  • Data Source:
  • BioGRID (affinity chromatography technology, two hybrid)

MCC

GTF2E2

Description MCC regulator of WNT signaling pathway general transcription factor IIE subunit 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Brain cytoarchitecture ( 20308991)
  • Cerebral amyloid angiopathy ( 25188341)
  • Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189)
  • Height ( 31562340)
  • Metabolite levels ( 23823483)
  • Neurofibrillary tangles ( 31497858)
  • Nicotine dependence symptom count ( 25555482)
  • Triglyceride levels ( 32203549)
  • Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes 80 interacting genes: ALDOB ANP32B APP BAAT C8orf33 C8orf48 CBX5 CBX8 CCDC112 CCDC146 CCDC180 CCDC185 CCDC187 CDC14B CDK8 CDKL3 CEP57L1 CEP95 CFAP58 CSNK1E CYLC2 DNAAF4 DYNC1I1 ELOA ERBIN ESRRG FAM161A FGF16 FRAT2 GTF2E2 HEMGN HSD17B3 IMP3 KAT5 KIF3C KIFC3 LRRC45 MAGEE1 MSANTD3 MTNR1A NANS NEK2 NFKBIB NOL12 PCCA PNKP POLL PRPF18 RASAL2 RCOR3 SEC61B SFRP4 SLTM SLU7 STOML2 SYT17 SYT6 TCEA2 TCEANC TGFB1 THAP7 TRMO TRMT2A TSHZ2 TSTD2 TXLNA UTP14C ZBTB48 ZNF12 ZNF189 ZNF202 ZNF264 ZNF3 ZNF35 ZNF417 ZNF438 ZNF497 ZNF543 ZNF648 ZNF792 26 interacting genes: APP ATF7IP CCNH CDK7 ERCC3 ERCC6 EXOC8 FOS GTF2A1 GTF2B GTF2E1 GTF2F1 GTF2F2 GTF2H1 JUN KAT5 KLF5 MCC MDM2 MNAT1 NUP62 PICK1 SND1 SUPT16H TBP XPA
Entrez ID 4163 2961
HPRD ID 01157 01800
Ensembl ID ENSG00000171444 ENSG00000197265
Uniprot IDs P23508 P29084
PDB IDs 6MTU 6MTV 1D8J 1D8K 5GPY 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 6O9L
Enriched GO Terms of Interacting Partners?
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