MCC and CDK8

  • Number of citations of the paper that reports this interaction (PubMedID 24412244)
  • 2
  • Data Source:
  • BioGRID (two hybrid)

MCC

CDK8

Description MCC regulator of WNT signaling pathway cyclin dependent kinase 8
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Brain cytoarchitecture ( 20308991)
  • Cerebral amyloid angiopathy ( 25188341)
  • Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189)
  • Height ( 31562340)
  • Metabolite levels ( 23823483)
  • Neurofibrillary tangles ( 31497858)
  • Nicotine dependence symptom count ( 25555482)
  • Triglyceride levels ( 32203549)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Immune response to measles-mumps-rubella vaccine ( 24811271)
  • Sporadic pituitary adenoma ( 26029870)
Interacting Genes 80 interacting genes: ALDOB ANP32B APP BAAT C8orf33 C8orf48 CBX5 CBX8 CCDC112 CCDC146 CCDC180 CCDC185 CCDC187 CDC14B CDK8 CDKL3 CEP57L1 CEP95 CFAP58 CSNK1E CYLC2 DNAAF4 DYNC1I1 ELOA ERBIN ESRRG FAM161A FGF16 FRAT2 GTF2E2 HEMGN HSD17B3 IMP3 KAT5 KIF3C KIFC3 LRRC45 MAGEE1 MSANTD3 MTNR1A NANS NEK2 NFKBIB NOL12 PCCA PNKP POLL PRPF18 RASAL2 RCOR3 SEC61B SFRP4 SLTM SLU7 STOML2 SYT17 SYT6 TCEA2 TCEANC TGFB1 THAP7 TRMO TRMT2A TSHZ2 TSTD2 TXLNA UTP14C ZBTB48 ZNF12 ZNF189 ZNF202 ZNF264 ZNF3 ZNF35 ZNF417 ZNF438 ZNF497 ZNF543 ZNF648 ZNF792 40 interacting genes: AURKA BCL6 BMPR1A BUB1 CCNC CCND1 CCNH CDH1 CDKN2B CTDP1 ERBB2 ERCC3 ESR1 ESR2 FLT1 FLT3 H3C14 KRAS MAML1 MBP MCC MED12 MED21 MED25 MED26 MED8 MED9 MLH3 MYC NRIP1 POLR2A PRMT5 SMAD2 SMAD3 SMARCA4 SREBF1 SUZ12 TOP1 TP53 WDR77
Entrez ID 4163 1024
HPRD ID 01157 04422
Ensembl ID ENSG00000171444 ENSG00000132964
Uniprot IDs P23508 P49336
PDB IDs 6MTU 6MTV 3RGF 4CRL 4F6S 4F6U 4F6W 4F70 4F7J 4F7L 4F7N 4F7S 4G6L 5BNJ 5CEI 5FGK 5HBE 5HBH 5HBJ 5HNB 5HVY 5I5Z 5ICP 5IDN 5IDP 5XQX 5XS2 6QTG 6QTJ 6R3S 6T41 6TPA 6Y0A
Enriched GO Terms of Interacting Partners?
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