RHOA and ARHGEF1

  • Number of citations of the paper that reports this interaction (PubMedID 28514442)
  • 406
  • Data Source:
  • BioGRID (affinity chromatography technology, enzymatic study, fluorescent resonance energy transfer)

RHOA

ARHGEF1

Description ras homolog family member A Rho guanine nucleotide exchange factor 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age at first sexual intercourse ( 34211149)
  • Blood protein levels ( 28240269)
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Cognitive function ( 25644384)
  • Coronary artery disease ( 29212778 28714974)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Cortical surface area (MOSTest) ( 32665545)
  • Crohn's disease ( 28067908)
  • Extremely high intelligence ( 29520040)
  • General cognitive ability ( 29844566)
  • Gut microbiota (functional units) ( 27694959)
  • Household income (MTAG) ( 31844048)
  • Inflammatory bowel disease ( 28067908)
  • Mood instability ( 31168069)
  • Morning person ( 30696823)
  • Refractive error ( 32231278)
  • Regular attendance at a religious group ( 29970889)
  • Sleep duration (short sleep) ( 30846698)
  • Subcortical volume (min-P) ( 32665545)
  • Subcortical volume (MOSTest) ( 32665545)
  • Ulcerative colitis ( 28067908)
  • Youthful appearance (self-reported) ( 32339537)
Interacting Genes 136 interacting genes: ACKR2 AGAP1 AGAP2 AKAP13 AMT ANKS1B ARAP2 ARF4 ARHGAP1 ARHGAP10 ARHGAP11A ARHGAP11B ARHGAP19 ARHGAP20 ARHGAP21 ARHGAP22 ARHGAP23 ARHGAP26 ARHGAP29 ARHGAP31 ARHGAP32 ARHGAP40 ARHGAP5 ARHGAP8 ARHGDIA ARHGDIB ARHGDIG ARHGEF1 ARHGEF10 ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF17 ARHGEF18 ARHGEF19 ARHGEF2 ARHGEF25 ARHGEF28 ARHGEF3 ARHGEF4 ARHGEF5 ARIH2 ARNTL BCR BIRC2 C1QA CAMP CAV1 CIT CLOCK CNKSR1 CNTNAP1 DAAM1 DCUN1D1 DEF6 DGKQ DIAPH1 DIAPH3 DLC1 DOCK7 DVL2 ENTPD3 FLNA FMN2 GMIP GPX1 HSPA1A ICMT IKBKG IKZF3 ITIH3 ITPR1 KCNA2 KCTD13 KLRG1 KTN1 LRP2 MCF2 MCF2L MPRIP MYO9A NET1 NGEF NOTCH1 OPHN1 OTUB1 PDCD10 PDE6D PITPNM1 PKN1 PKN2 PLCG1 PLD1 PLEKHG2 PLEKHG4 PLEKHG6 PPP1R12A PREX1 PREX2 PRKACA PRKCA PRKCZ PTPRF RABAC1 RACK1 RAP1GDS1 RASGRF1 RASGRF2 RASSF1 RHPN1 RHPN2 RIPK4 RIPOR2 RIPOR3 ROCK1 RPN2 RTKN SH3BP1 SLC13A1 SMAD2 SMURF1 SMURF2 SPRED2 SRGAP1 STARD8 SUB1 TGFBR1 TGM2 TIAM1 TNFAIP1 TRIO TRIP6 TRPC1 VAV1 VAV2 VAV3 11 interacting genes: ATR CD44 CNKSR1 CSNK1E GNA13 HRAS PRKCA RAP1A RHOA SREBF2 TCF4
Entrez ID 387 9138
HPRD ID 01323 03511
Ensembl ID ENSG00000067560 ENSG00000076928
Uniprot IDs A0A024R324 A0A7I2YQV1 B4DKN9 C9JRM1 C9JX21 P61586 Q9BVT0 A0A024R0R1 Q92888
PDB IDs 1A2B 1CC0 1CXZ 1DPF 1FTN 1KMQ 1LB1 1OW3 1S1C 1TX4 1X86 1XCG 2RGN 3KZ1 3LW8 3LWN 3LXR 3MSX 3T06 4D0N 4XH9 4XOI 4XSG 4XSH 5A0F 5BWM 5C2K 5C4M 5EZ6 5FR1 5FR2 5HPY 5IRC 5JCP 5JHG 5JHH 5M6X 5M70 5ZHX 6BC0 6BCA 6BCB 6KX2 6KX3 6R3V 6V6M 6V6U 6V6V 1IAP 1SHZ 3AB3 3ODO 3ODW 3ODX 3P6A
Enriched GO Terms of Interacting Partners?
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