ISL1 and LDB2

  • Number of citations of the paper that reports this interaction (PubMedID 20211142)
  • 361
  • Data Source:
  • BioGRID (two hybrid)

ISL1

LDB2

Description ISL LIM homeobox 1 LIM domain binding 2
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Age at first sexual intercourse ( 34211149)
  • Alcohol use disorder (consumption score) ( 30940813)
  • Automobile speeding propensity ( 30643258)
  • Brain morphology (MOSTest) ( 32665545)
  • Childhood body mass index ( 33045005)
  • Childhood ear infection ( 27182965)
  • Classic bladder exstrophy ( 25763902)
  • Cortical surface area (MOSTest) ( 32665545)
  • Dental caries ( 23259602)
  • Diastolic blood pressure ( 27841878)
  • Emotional lability in attention deficit hyperactivity disorder ( 31085060)
  • General risk tolerance (MTAG) ( 30643258)
  • Haemorrhoidal disease ( 33888516)
  • Heel bone mineral density ( 30598549)
  • QT interval ( 29213071)
  • Risk-taking tendency (4-domain principal component model) ( 30643258)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Subcortical volume (MOSTest) ( 32665545)
  • Systolic blood pressure ( 27841878)
  • Verbal declarative memory ( 25648963)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Change in LVEF in response to paclitaxel and trastuzumab in HER2+ breast cancer ( 28763429)
  • glucocorticoid receptor gene expression in B-cell precursor acute lymphoblastic leukaemia ( 33002292)
  • Liver fibrosis (total hepatic collagen content) ( 32953199)
  • Number of sexual partners ( 30643258)
  • QT interval ( 23534349)
  • Rhegmatogenous retinal detachment ( 23585552)
  • Systemic juvenile idiopathic arthritis ( 27927641)
  • Waist circumference ( 28552196)
Interacting Genes 22 interacting genes: ADCY2 APP CDK6 CDKN2B CRK ESR1 HNF4A ISL2 KDM1A LDB1 LDB2 LHX1 LHX3 LMO2 LMX1A NR2F1 PECR PLCG2 RELA RLIM SMAD3 ZNF511 29 interacting genes: C14orf119 CETN3 DGCR6L EGLN3 EPM2AIP1 EXOC3L1 GGACT HDAC7 ISL1 LHX4 LHX8 LHX9 LMO1 LMO2 LMO3 LMO4 LNX1 NTAQ1 PSMB1 RASIP1 RILP RLIM SDCBP SMARCD1 SSBP2 SSBP3 SSBP4 TSNAX TTC19
Entrez ID 3670 9079
HPRD ID 02650 16022
Ensembl ID ENSG00000016082 ENSG00000169744
Uniprot IDs P61371 B7Z6D0 E9PFI4 G5E9Y7 O43679
PDB IDs
Enriched GO Terms of Interacting Partners?
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