ISL1 and CDKN2B

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 87
  • Data Source:
  • BioGRID (two hybrid)

ISL1

CDKN2B

Description ISL LIM homeobox 1 cyclin dependent kinase inhibitor 2B
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Age at first sexual intercourse ( 34211149)
  • Alcohol use disorder (consumption score) ( 30940813)
  • Automobile speeding propensity ( 30643258)
  • Brain morphology (MOSTest) ( 32665545)
  • Childhood body mass index ( 33045005)
  • Childhood ear infection ( 27182965)
  • Classic bladder exstrophy ( 25763902)
  • Cortical surface area (MOSTest) ( 32665545)
  • Dental caries ( 23259602)
  • Diastolic blood pressure ( 27841878)
  • Emotional lability in attention deficit hyperactivity disorder ( 31085060)
  • General risk tolerance (MTAG) ( 30643258)
  • Haemorrhoidal disease ( 33888516)
  • Heel bone mineral density ( 30598549)
  • QT interval ( 29213071)
  • Risk-taking tendency (4-domain principal component model) ( 30643258)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Subcortical volume (MOSTest) ( 32665545)
  • Systolic blood pressure ( 27841878)
  • Verbal declarative memory ( 25648963)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes 22 interacting genes: ADCY2 APP CDK6 CDKN2B CRK ESR1 HNF4A ISL2 KDM1A LDB1 LDB2 LHX1 LHX3 LMO2 LMX1A NR2F1 PECR PLCG2 RELA RLIM SMAD3 ZNF511 65 interacting genes: AKT1 APP ARAF ARNT ARPC3 ATP6V1H BECN1 CBLC CCDC33 CCDC90B CCNC CCND2 CCNE1 CD44 CDK17 CDK4 CDK6 CDK8 CDKN2A CDKN2C CEP126 CNKSR3 ELAVL2 ELP1 EPHA2 ERBB2 FGFR4 FZR1 GLIS2 GRM1 HGF HIF1A IGF1R INCA1 ISL1 KAT2A KDELR2 LATS2 MAGEA11 MAP2K3 MAP2K5 MAP2K6 MDM4 MET MYC NF2 NIF3L1 PDGFRA PICK1 PYCR3 RAF1 RASSF1 RTL8C RUSC1 SPG21 STK11 TEAD2 TERT TGFB1I1 TNFRSF1A TP53 TRAF1 TSC1 TTYH2 ZBTB17
Entrez ID 3670 1030
HPRD ID 02650 02696
Ensembl ID ENSG00000016082 ENSG00000147883
Uniprot IDs P61371 K7PPU3 P42772
PDB IDs
Enriched GO Terms of Interacting Partners?
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