INSIG1 and HTR2B

  • Number of citations of the paper that reports this interaction (PubMedID 28298427)
  • 23
  • Data Source:
  • BioGRID (two hybrid)

INSIG1

HTR2B

Description insulin induced gene 1 5-hydroxytryptamine receptor 2B
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bladder cancer (smoking interaction) ( 24662972)
  • Diverticular disease ( 30177863)
  • Energy expenditure (24h) ( 28476931)
  • Formal thought disorder in schizophrenia ( 22648509)
  • Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681)
  • Plasma anti-thyroglobulin levels ( 29678681)
  • Triiodothyronine levels and thyroxine levels ( 30843173)
  • Proportion of activated microglia (midfrontal cortex) ( 30679421)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes 12 interacting genes: AQP6 BDKRB1 ELOC HMGCR HTR2B PCK1 PSMA7 PSMC3 SCAP SREBF2 TMEM237 VCP 27 interacting genes: ABCA3 ATP1B1 BNIP3 BNIP3L CBR1 CHPT1 G6PC3 GNA11 GNAQ HAT1 HDGFL2 INSIG1 KIF19 LNX1 MATR3 METRN NAT14 NIPA2 OAZ1 PLLP PPP1R3F RAE1 SLC31A2 SLC37A1 SLC44A2 SNTA1 TRAM1L1
Entrez ID 3638 3357
HPRD ID 03633 03077
Ensembl ID ENSG00000186480 ENSG00000135914
Uniprot IDs A0A024RD68 A4D2M9 F5H6P3 O15503 P41595
PDB IDs 4J81 4IB4 4NC3 5TUD 5TVN 6DRX 6DRY 6DRZ 6DS0
Enriched GO Terms of Interacting Partners?
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