IFNL2 and IL10RB

Number of citations of the paper that reports this interaction (PubMedID 12469119)
542

Data Source:
HPRD (in vivo)

		IFNL2	IL10RB
Description		interferon lambda 2	interleukin 10 receptor subunit beta
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Integral Component Of Membrane Interleukin-28 Receptor Complex
	Molecular Function	Signaling Receptor Binding Cytokine Activity	Cytokine Receptor Activity Interleukin-10 Receptor Activity Protein Binding Signaling Receptor Activity
	Biological Process	Mucosal Immune Response Receptor Signaling Pathway Via JAK-STAT Innate Immune Response Positive Regulation Of Immune Response Defense Response To Virus	Inflammatory Response Immune Response Signal Transduction Cytokine-mediated Signaling Pathway Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Defense Response To Virus Positive Regulation Of Cellular Respiration
Pathways		Interleukin-20 family signaling	Other interleukin signaling Interleukin-10 signaling Interleukin-20 family signaling
Drugs
Diseases
GWAS		Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Leukocyte telomere length ( 32109421)	Blood protein levels ( 30072576) Crohn's disease ( 23128233) Multiple sclerosis ( 31604244) Narcolepsy ( 24204295 23459209)
Interacting Genes		2 interacting genes: IFNLR1 IL10RB	9 interacting genes: CBR3 IFNL2 IFNL3 IL10 IL10RA IL22 RCAN1 UCN2 UCN3
Entrez ID		282616	3588
HPRD ID		09586	00473
Ensembl ID		ENSG00000183709	ENSG00000243646
Uniprot IDs		Q8IZJ0	Q08334
PDB IDs			3LQM 5T5W
Enriched GO Terms of Interacting Partners?
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