CPLX4 and DEFB127

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CPLX4	DEFB127
Description		complexin 4	defensin beta 127
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane SNARE Complex Terminal Bouton	Cellular_component Extracellular Region
	Molecular Function	SNARE Binding Protein Binding Syntaxin Binding	Protein Binding
	Biological Process	Visual Perception Synaptic Vesicle Exocytosis Regulation Of Neurotransmitter Secretion Response To Stimulus	Defense Response To Bacterium Innate Immune Response Defense Response To Gram-negative Bacterium Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways			Beta defensins Defensins
Drugs
Diseases
GWAS		Cardiac troponin-I levels ( 31014085) Chronotype ( 27494321) Macular thickness ( 30535121) Morning vs. evening chronotype ( 27494321)	Coronary artery disease in type 1 diabetes ( 32077919)
Interacting Genes		92 interacting genes: ADIPOQ AGTRAP AIG1 AOC3 APOD AQP1 AQP9 ASGR1 ATP6V0C BNIP2 C14orf180 C1GALT1 C3orf52 C5 CACNG1 CCL4L2 CD81 CDIPT CDS2 CLDND2 CLEC4G CLN6 CMTM5 CNIH1 CTSA CTXN3 CYB5B CYBC1 CYP4F2 DEFB127 EMD GAD2 GIMAP1 GRM2 HACD1 HHATL HMOX1 INSIG2 LPAR3 MAL MALL MAN2B2 MGAM NINJ2 NRM ORMDL1 PGAP2 PLN PLP2 PLPP4 PNLIPRP1 PTPN9 RTP2 SEC22B SELENOK SFTPC SLC30A2 SLC30A8 SLC35A1 SLC35A4 SLC35B4 SLC38A7 SLC39A9 SMCO4 STX3 STX8 SYNJ2BP TF TMEM120B TMEM14A TMEM14B TMEM19 TMEM201 TMEM203 TMEM218 TMEM229B TMEM243 TMEM254 TMEM267 TMEM60 TMEM79 TMEM86A TMEM97 TRAF3IP3 TSPO2 UBIAD1 VAMP4 VAMP5 VKORC1 WFDC2 YIPF6 ZFPL1	14 interacting genes: AQP6 ASZ1 AURKAIP1 BCL2L13 CD79A CPLX4 EBP FAM174A FCER1G LMNA MFSD14B MMGT1 PIANP TFEC
Entrez ID		339302	140850
HPRD ID		13091	10877
Ensembl ID		ENSG00000166569	ENSG00000088782
Uniprot IDs		Q7Z7G2	Q9H1M4
PDB IDs
Enriched GO Terms of Interacting Partners?
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