DEFB127 and BCL2L13

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		DEFB127	BCL2L13
Description		defensin beta 127	BCL2 like 13
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Extracellular Region	Nucleus Mitochondrion Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding	Protein Binding Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process
	Biological Process	Defense Response To Bacterium Innate Immune Response Defense Response To Gram-negative Bacterium Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Apoptotic Process
Pathways		Beta defensins Defensins
Drugs
Diseases
GWAS		Coronary artery disease in type 1 diabetes ( 32077919)	Baseline cortisol levels in response to low dose short synacthen test in corticosteroid treated asthma ( 29551627) Eosinophil counts ( 32888494) Granulocyte count ( 27863252) Hemoglobin levels ( 32327693) Interleukin-10 levels ( 22205395) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494)
Interacting Genes		14 interacting genes: AQP6 ASZ1 AURKAIP1 BCL2L13 CD79A CPLX4 EBP FAM174A FCER1G LMNA MFSD14B MMGT1 PIANP TFEC	56 interacting genes: ADIPOQ AGTRAP AIG1 APOD APP AQP1 BET1 C4orf3 CD53 CLDN19 CRB3 DEFB127 ERG28 ERMP1 FAM210B FXYD3 FZD7 GABARAPL2 GALNT2 GAST HMOX2 IL17RA JAGN1 LAT LPAR3 MAL MTNR1B NINJ2 PLLP PLN PLP1 PLPP4 SLC30A8 SLC35A1 SLC35G5 SMIM1 SPOCK1 STX12 STX8 TM6SF2 TMEM128 TMEM14C TMEM242 TMEM254 TMEM51 TMEM72 TMEM86A TMEM86B TMEM97 TMUB2 TNF TNMD TRARG1 UPK1B VAMP3 VAMP4
Entrez ID		140850	23786
HPRD ID		10877	09822
Ensembl ID		ENSG00000088782	ENSG00000099968
Uniprot IDs		Q9H1M4	A0A087WTL4 A0A087WW80 A0A087WX97 A0A0A0MR90 A8K5Y4 B2RB43 B7Z238 B7Z737 E9PDD6 F6VJB4 Q86T62 Q9BXK5
PDB IDs			2IPD
Enriched GO Terms of Interacting Partners?
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