DEFB127 and TFEC

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		DEFB127	TFEC
Description		defensin beta 127	transcription factor EC
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Extracellular Region	Chromatin Nucleus Nucleoplasm
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Defense Response To Bacterium Innate Immune Response Defense Response To Gram-negative Bacterium Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cellular Response To Heat Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Beta defensins Defensins
Drugs
Diseases
GWAS		Coronary artery disease in type 1 diabetes ( 32077919)	Body mass index ( 28892062) Chronotype ( 30696823) General risk tolerance (MTAG) ( 30643258) Height ( 28552196) Intraocular pressure ( 29617998 29785010 29235454) Number of sexual partners ( 30643258) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Schizophrenia, bipolar disorder or major depressive disorder ( 34099189) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189) Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189) Tonsillectomy ( 27182965 28928442)
Interacting Genes		14 interacting genes: AQP6 ASZ1 AURKAIP1 BCL2L13 CD79A CPLX4 EBP FAM174A FCER1G LMNA MFSD14B MMGT1 PIANP TFEC	11 interacting genes: DCK DEFB127 HNRNPA1 LPAR3 MITF NAPB SMCO4 TET2 TFE3 TFEB ZMAT2
Entrez ID		140850	22797
HPRD ID		10877	05294
Ensembl ID		ENSG00000088782	ENSG00000105967
Uniprot IDs		Q9H1M4	O14948
PDB IDs
Enriched GO Terms of Interacting Partners?
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