GZMB and CHRM3

  • Number of citations of the paper that reports this interaction (PubMedID 11665980)
  • 19
  • Data Source:
  • HPRD (in vitro, in vivo)

GZMB

CHRM3

Description granzyme B cholinergic receptor muscarinic 3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic obstructive pulmonary disease ( 30804561)
  • Colorectal cancer ( 29228715)
  • Depression in smokers ( 30219690)
  • Electroencephalogram traits ( 25387704)
  • Feeling worry ( 29500382)
  • FEV1 ( 30804560)
  • Generalized epilepsy ( 22949513)
  • Gut microbiota beta diversity (weighted UniFrac distance) ( 33208821)
  • Hallucinations in long-term cannabis use ( 31740666)
  • Hypertension ( 17554300)
  • Interleukin-6 (red blood cell fatty acid level interaction) ( 28820441)
  • Lung function (FEV1/FVC) ( 28166213 30804560)
  • Peak expiratory flow ( 30804560)
  • Platelet count ( 21507922)
  • Post bronchodilator FEV1 ( 26634245)
  • Reflection (response to stress) ( 30886212)
  • Sulfasalazine-induced agranulocytosis ( 28762467)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes 27 interacting genes: BID CASP3 CASP7 CASP8 CASP9 CD2AP CHRM3 DFFA GRIA3 IGF2R LMNA LMNB1 NEK9 PARP1 PRF1 PRKDC PTGES3 PTK2 RAB27A SERPINB9 SRGN TUBA1A UBE4A UBE4B XRCC4 XRCC5 XRCC6 26 interacting genes: ARF1 ARF6 BSG CALM3 CCDC184 CD2BP2 COMMD7 CSNK1A1 GNAQ GNAS GPRASP1 GRK6 GZMB JAKMIP1 MAGED2 PDGFRB POM121C PPP1R9B RAB5IF RGS7 SEPTIN3 SET SGSM3 TAP1 TPM3 YIPF3
Entrez ID 3002 1131
HPRD ID 00476 00329
Ensembl ID ENSG00000100453 ENSG00000133019
Uniprot IDs J3KQ52 P10144 Q67BC3 Q6XGZ4 A0A024R3W1 P20309
PDB IDs 1FQ3 1IAU 2CSA
Enriched GO Terms of Interacting Partners?
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