CHRM3 and GRK6

  • Number of citations of the paper that reports this interaction (PubMedID 11856737)
  • 19
  • Data Source:
  • HPRD (in vitro)

CHRM3

GRK6

Description cholinergic receptor muscarinic 3 G protein-coupled receptor kinase 6
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic obstructive pulmonary disease ( 30804561)
  • Colorectal cancer ( 29228715)
  • Depression in smokers ( 30219690)
  • Electroencephalogram traits ( 25387704)
  • Feeling worry ( 29500382)
  • FEV1 ( 30804560)
  • Generalized epilepsy ( 22949513)
  • Gut microbiota beta diversity (weighted UniFrac distance) ( 33208821)
  • Hallucinations in long-term cannabis use ( 31740666)
  • Hypertension ( 17554300)
  • Interleukin-6 (red blood cell fatty acid level interaction) ( 28820441)
  • Lung function (FEV1/FVC) ( 28166213 30804560)
  • Peak expiratory flow ( 30804560)
  • Platelet count ( 21507922)
  • Post bronchodilator FEV1 ( 26634245)
  • Reflection (response to stress) ( 30886212)
  • Sulfasalazine-induced agranulocytosis ( 28762467)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
  • Activated partial thromboplastin time ( 22703881)
  • Blood protein levels ( 28240269)
  • Cardiac troponin-I levels ( 31014085)
  • Chronic kidney disease ( 20383146)
  • Extremely high intelligence ( 29520040)
  • Glycine levels ( 30837465)
  • Intelligence (MTAG) ( 29326435)
  • Metabolite levels ( 22916037)
  • Neutrophil percentage of white cells ( 32888494)
  • Tinnitus ( 33742053)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 26 interacting genes: ARF1 ARF6 BSG CALM3 CCDC184 CD2BP2 COMMD7 CSNK1A1 GNAQ GNAS GPRASP1 GRK6 GZMB JAKMIP1 MAGED2 PDGFRB POM121C PPP1R9B RAB5IF RGS7 SEPTIN3 SET SGSM3 TAP1 TPM3 YIPF3 19 interacting genes: ADRB2 BDKRB2 CHRM3 EDNRA EDNRB FBXO7 FSHR GIT1 ITGA5 KCNIP3 LTB4R PRSS23 RCVRN RHO SLC9A3R1 SNCA SNCB SNCG TBXA2R
Entrez ID 1131 2870
HPRD ID 00329 02925
Ensembl ID ENSG00000133019 ENSG00000198055
Uniprot IDs A0A024R3W1 P20309 B3KPS5 P43250
PDB IDs 2CSA 2ACX 3NYN 3NYO
Enriched GO Terms of Interacting Partners?
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