OSGIN1 and PDE4C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		OSGIN1	PDE4C
Description		oxidative stress induced growth inhibitor 1	phosphodiesterase 4C
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component	Extracellular Space Nucleus Cytosol Cilium Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Growth Factor Activity	3',5'-cyclic-nucleotide Phosphodiesterase Activity 3',5'-cyclic-AMP Phosphodiesterase Activity Metal Ion Binding
	Biological Process	Signal Transduction Cell Differentiation Negative Regulation Of Cell Growth Regulation Of Cell Migration Regulation Of Cell Population Proliferation Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process	CAMP Catabolic Process Signal Transduction
Pathways			DARPP-32 events G alpha (s) signalling events
Drugs			Caffeine Dyphylline Iloprost Amrinone Roflumilast Piclamilast Crisaborole Ibudilast Exisulind Trapidil
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) LDL cholesterol ( 30275531) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (alkaline phosphatase) ( 33972514) Pursuit maintenance gain ( 29064472) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Serum alkaline phosphatase levels ( 33547301)	Abdominal subcutaneous adipose tissue volume ( 34128465) Apolipoprotein B levels ( 32203549) Body shape index ( 34021172) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Urate levels ( 31578528) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		47 interacting genes: AKT1 ARNT2 ATM BCAR3 BEND7 BTBD2 CAPN3 CCDC33 CENPN CRX DECR2 DNAJA3 FGFR4 GCLM HOMEZ IKBKG IKZF3 INCA1 KATNBL1 KRAS KRT75 LNX1 MEI4 MEIS2 MEOX1 MEOX2 MTERF4 PAX5 PDE4A PDE4C PICK1 POLDIP3 POLR2G PPM1D PTEN REL SAXO1 SMARCB1 SORBS3 TCF12 TCF4 TLE5 TRIM54 XRCC3 ZBTB42 ZC2HC1C ZKSCAN4	10 interacting genes: DDIT4L GDF15 GSC2 KLRK1 MEOX1 MEOX2 OSGIN1 PAX6 SRI ZNF280A
Entrez ID		29948	5143
HPRD ID		06412	02529
Ensembl ID		ENSG00000140961	ENSG00000105650
Uniprot IDs		Q9UJX0	O43849 P78505 Q08493 Q32MM7 Q7KYS4
PDB IDs			1LXU 2QYM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
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