PDE4C and ZNF280A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PDE4C	ZNF280A
Description		phosphodiesterase 4C	zinc finger protein 280A
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytosol Cilium Perinuclear Region Of Cytoplasm	Nucleus
	Molecular Function	3',5'-cyclic-nucleotide Phosphodiesterase Activity 3',5'-cyclic-AMP Phosphodiesterase Activity Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	CAMP Catabolic Process Signal Transduction	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II
Pathways		DARPP-32 events G alpha (s) signalling events
Drugs		Caffeine Dyphylline Iloprost Amrinone Roflumilast Piclamilast Crisaborole Ibudilast Exisulind Trapidil
Diseases
GWAS		Abdominal subcutaneous adipose tissue volume ( 34128465) Apolipoprotein B levels ( 32203549) Body shape index ( 34021172) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Urate levels ( 31578528) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Metabolite levels ( 23823483)
Interacting Genes		10 interacting genes: DDIT4L GDF15 GSC2 KLRK1 MEOX1 MEOX2 OSGIN1 PAX6 SRI ZNF280A	8 interacting genes: CABP5 CALM1 CALM2 CALM3 EIF1AD ENOPH1 KDM1A PDE4C
Entrez ID		5143	129025
HPRD ID		02529	18129
Ensembl ID		ENSG00000105650	ENSG00000169548
Uniprot IDs		O43849 P78505 Q08493 Q32MM7 Q7KYS4	A0A0G2JN84 P59817
PDB IDs		1LXU 2QYM
Enriched GO Terms of Interacting Partners?
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