OSGIN1 and DECR2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		OSGIN1	DECR2
Description		oxidative stress induced growth inhibitor 1	2,4-dienoyl-CoA reductase 2
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component	Peroxisomal Membrane Cytosol
	Molecular Function	Protein Binding Growth Factor Activity	Protein Binding 2,4-dienoyl-CoA Reductase (NADPH) Activity Trans-2-enoyl-CoA Reductase (NADPH) Activity
	Biological Process	Signal Transduction Cell Differentiation Negative Regulation Of Cell Growth Regulation Of Cell Migration Regulation Of Cell Population Proliferation Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process	Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase
Pathways			Beta-oxidation of very long chain fatty acids Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) LDL cholesterol ( 30275531) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (alkaline phosphatase) ( 33972514) Pursuit maintenance gain ( 29064472) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Serum alkaline phosphatase levels ( 33547301)	Body mass index ( 26426971) Hodgkin's lymphoma ( 34216518) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		47 interacting genes: AKT1 ARNT2 ATM BCAR3 BEND7 BTBD2 CAPN3 CCDC33 CENPN CRX DECR2 DNAJA3 FGFR4 GCLM HOMEZ IKBKG IKZF3 INCA1 KATNBL1 KRAS KRT75 LNX1 MEI4 MEIS2 MEOX1 MEOX2 MTERF4 PAX5 PDE4A PDE4C PICK1 POLDIP3 POLR2G PPM1D PTEN REL SAXO1 SMARCB1 SORBS3 TCF12 TCF4 TLE5 TRIM54 XRCC3 ZBTB42 ZC2HC1C ZKSCAN4	11 interacting genes: APP C14orf119 EP300 NEDD4L OSGIN1 PEX5 TRIM55 TRIM63 UBC USP11 VPS26C
Entrez ID		29948	26063
HPRD ID		06412	16789
Ensembl ID		ENSG00000140961	ENSG00000242612
Uniprot IDs		Q9UJX0	Q9NUI1
PDB IDs			4FC6 4FC7
Enriched GO Terms of Interacting Partners?
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