NCAPH2 and TMEM120B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NCAPH2	TMEM120B
Description		non-SMC condensin II complex subunit H2	transmembrane protein 120B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Condensin Complex Nucleus Nucleoplasm Membrane Cell Junction Intercellular Bridge	Cellular_component Nuclear Inner Membrane Membrane Integral Component Of Membrane
	Molecular Function	Chromatin Binding Protein Binding	Molecular_function Ion Channel Activity Protein Binding
	Biological Process	Mitotic Chromosome Condensation Meiotic Chromosome Condensation T Cell Differentiation In Thymus Mitotic Sister Chromatid Separation Female Meiosis Chromosome Separation	Biological_process Fat Cell Differentiation Protein Heterooligomerization
Pathways		Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS		B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Cerebrospinal fluid clusterin levels ( 26545630) Chronic lymphocytic leukemia ( 28165464) Mean corpuscular hemoglobin ( 32888494 20139978) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell traits ( 23222517) Serum metabolite levels ( 33031748)	Blood protein levels ( 29875488) HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 24026423 32888494 27863252) Mean reticulocyte volume ( 32888494) Molybdenum levels ( 26025379) Neutrophil count ( 32888494) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494 27863252) White blood cell count ( 32888494)
Interacting Genes		25 interacting genes: ACTN2 ANKRD46 APOD C4orf3 CTXN3 EGLN3 EMD FDFT1 FOLR1 IGFBP5 LMO2 MAL ODAD4 PRPF31 SNRPC SUMO2 TMEM120B TMEM14C TMEM86A TRAF2 TTC32 TUBB UBIAD1 USHBP1 VAMP5	58 interacting genes: ALOX5AP ANKS6 APOA5 AQP6 AQP8 BNIP3L CCNDBP1 CD74 COMT CPLX4 CREB3L1 DNAH10 EBP ERGIC3 FCER1G FFAR2 FKBP7 GAD2 GJB1 GORAB GPR152 GPRC5D GPX8 HSD17B11 IFNGR2 IL7R JAGN1 JPH1 KCNJ6 LMNA LRRTM2 MGST3 MRPS18B MTRFR MUC1 NCAPH2 REEP2 REEP4 RETREG3 RNF19B RNF5 SCN3B SH3GL3 SLC10A1 SLC10A6 SLC17A8 SLC18A1 SLC1A3 STOM STX2 TLCD4 TMEM139 TMEM143 TMEM14B TMEM80 TMPRSS2 TMX2 ZDHHC15
Entrez ID		29781	144404
HPRD ID		11783	19119
Ensembl ID		ENSG00000025770	ENSG00000188735
Uniprot IDs		Q6IBW4	A0PK00
PDB IDs
Enriched GO Terms of Interacting Partners?
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