TMEM120B and LRRTM2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM120B	LRRTM2
Description		transmembrane protein 120B	leucine rich repeat transmembrane neuronal 2
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Nuclear Inner Membrane Membrane Integral Component Of Membrane	Extracellular Space Excitatory Synapse Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse GABA-ergic Synapse Integral Component Of Postsynaptic Specialization Membrane Integral Component Of Postsynaptic Density Membrane
	Molecular Function	Molecular_function Ion Channel Activity Protein Binding	Protein Binding Neurexin Family Protein Binding
	Biological Process	Biological_process Fat Cell Differentiation Protein Heterooligomerization	Negative Regulation Of Receptor Internalization Synapse Organization Positive Regulation Of Synapse Assembly Long-term Synaptic Potentiation Regulation Of Postsynaptic Density Assembly
Pathways			Neurexins and neuroligins
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 24026423 32888494 27863252) Mean reticulocyte volume ( 32888494) Molybdenum levels ( 26025379) Neutrophil count ( 32888494) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494 27863252) White blood cell count ( 32888494)	Malaria ( 31844061)
Interacting Genes		58 interacting genes: ALOX5AP ANKS6 APOA5 AQP6 AQP8 BNIP3L CCNDBP1 CD74 COMT CPLX4 CREB3L1 DNAH10 EBP ERGIC3 FCER1G FFAR2 FKBP7 GAD2 GJB1 GORAB GPR152 GPRC5D GPX8 HSD17B11 IFNGR2 IL7R JAGN1 JPH1 KCNJ6 LMNA LRRTM2 MGST3 MRPS18B MTRFR MUC1 NCAPH2 REEP2 REEP4 RETREG3 RNF19B RNF5 SCN3B SH3GL3 SLC10A1 SLC10A6 SLC17A8 SLC18A1 SLC1A3 STOM STX2 TLCD4 TMEM139 TMEM143 TMEM14B TMEM80 TMPRSS2 TMX2 ZDHHC15	2 interacting genes: TMEM120B TNF
Entrez ID		144404	26045
HPRD ID		19119	17454
Ensembl ID		ENSG00000188735	ENSG00000146006
Uniprot IDs		A0PK00	O43300
PDB IDs			5Z8X 5Z8Y
Enriched GO Terms of Interacting Partners?
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