GRIK5 and MLF1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GRIK5	MLF1
Description		glutamate ionotropic receptor kainate type subunit 5	myeloid leukemia factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Plasma Membrane Dendrite Kainate Selective Glutamate Receptor Complex Terminal Bouton Perikaryon Postsynaptic Membrane Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse Integral Component Of Presynaptic Membrane Integral Component Of Postsynaptic Density Membrane	Nucleus Cytoplasm Cilium Ciliary Basal Body
	Molecular Function	Glutamate Receptor Activity Ligand-gated Ion Channel Activity Kainate Selective Glutamate Receptor Activity SH3 Domain Binding PDZ Domain Binding Signaling Receptor Activity Identical Protein Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	DNA Binding Protein Binding Protein Domain Specific Binding
	Biological Process	Protein Retention In ER Lumen Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Ion Transmembrane Transport Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Receptor Clustering Positive Regulation Of Neuron Apoptotic Process Modulation Of Chemical Synaptic Transmission Establishment Of Localization In Cell Excitatory Postsynaptic Potential Cellular Response To Glucose Stimulus	Myeloid Progenitor Cell Differentiation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Cell Cycle
Pathways		Activation of Ca-permeable Kainate Receptor
Drugs		Glutamic acid Butabarbital Topiramate
Diseases
GWAS		Bipolar disorder ( 21771265) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lymphocyte counts ( 32888494) Meat-related diet ( 32066663)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Depression ( 29700475) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Major depressive disorder ( 27479909) PR interval ( 32439900) Sporadic neuroblastoma ( 28545128) Systolic blood pressure ( 30224653)
Interacting Genes		8 interacting genes: DLG4 GOLM1 GPAA1 GRID2 GRIK2 GRIK3 LRSAM1 MLF1	14 interacting genes: CENPU CLRN1 COP1 COPS3 DNAJB6 GBA GMPS GRIK5 MAGEA11 MEOX2 NRBP1 RARRES1 RNF13 YWHAZ
Entrez ID		2901	4291
HPRD ID		02614	03239
Ensembl ID		ENSG00000105737	ENSG00000178053
Uniprot IDs		Q16478	A0A0S2Z4U8 A0A140VKD2 B2RD48 P58340 Q2TLE4 Q5HYH4
PDB IDs			3UAL 3UBW 6Y8E
Enriched GO Terms of Interacting Partners?
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