GRIK5 and GOLM1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		GRIK5	GOLM1
Description		glutamate ionotropic receptor kainate type subunit 5	golgi membrane protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Plasma Membrane Dendrite Kainate Selective Glutamate Receptor Complex Terminal Bouton Perikaryon Postsynaptic Membrane Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse Integral Component Of Presynaptic Membrane Integral Component Of Postsynaptic Density Membrane	Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Integral Component Of Plasma Membrane
	Molecular Function	Glutamate Receptor Activity Ligand-gated Ion Channel Activity Kainate Selective Glutamate Receptor Activity SH3 Domain Binding PDZ Domain Binding Signaling Receptor Activity Identical Protein Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	Protein Binding
	Biological Process	Protein Retention In ER Lumen Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Ion Transmembrane Transport Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Receptor Clustering Positive Regulation Of Neuron Apoptotic Process Modulation Of Chemical Synaptic Transmission Establishment Of Localization In Cell Excitatory Postsynaptic Potential Cellular Response To Glucose Stimulus	Nucleus Organization Regulation Of Lipid Metabolic Process
Pathways		Activation of Ca-permeable Kainate Receptor	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs		Glutamic acid Butabarbital Topiramate
Diseases
GWAS		Bipolar disorder ( 21771265) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lymphocyte counts ( 32888494) Meat-related diet ( 32066663)	Blood protein levels ( 30072576) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		8 interacting genes: DLG4 GOLM1 GPAA1 GRID2 GRIK2 GRIK3 LRSAM1 MLF1	79 interacting genes: ABI3 AIG1 ANKRD46 ARTN ASPH B3GNT4 BCL2L1 C1orf174 C1QL4 CDIPT CIAO1 CLDN4 CLDND2 CLK1 CNPY3 DCK DCTN2 DESI1 DEXI EFTUD2 EIF2B3 EIF3J ELAC2 FLOT1 FTH1 FUT9 GALNT15 GAST GEMIN7 GET3 GLB1 GRIK5 GUCA2A HGFAC HMGB1 HSD17B13 IGFBP5 INSIG2 JAGN1 KCNE3 LAT LSM12 MED22 MIP NDUFV2 NEU1 NINJ1 NIPSNAP3A NRSN2 PGRMC1 RACK1 RIPPLY2 RPA2 RPL13A SFTPC SLC13A5 SLC30A3 SLC35B2 SLC40A1 SLC5A4 SLCO3A1 ST6GAL2 STRIT1 SYT1 TF THSD7A TLE1 TMEM109 TMEM140 TMEM147 TMEM176A TMEM86B TMEM98 TMPO TMUB1 TMUB2 TSG101 VSTM1 ZFAND3
Entrez ID		2901	51280
HPRD ID		02614	08428
Ensembl ID		ENSG00000105737	ENSG00000135052
Uniprot IDs		Q16478	B3KNK9 Q8NBJ4
PDB IDs
Enriched GO Terms of Interacting Partners?
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