GLRB and GPHN

Number of citations of the paper that reports this interaction (PubMedID 7546736)
128

Data Source:
HPRD (in vivo, in vitro)

		GLRB	GPHN
Description		glycine receptor beta	gephyrin
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Glycine-gated Chloride Channel Complex Dendrite Neuron Projection Synapse Postsynaptic Membrane Glycinergic Synapse GABA-ergic Synapse	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Postsynaptic Density Dendrite Postsynaptic Membrane Synaptic Membrane Anchored Component Of Synaptic Membrane Postsynaptic Specialization Postsynaptic Specialization Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Chloride Channel Activity Protein Binding Glycine Binding Extracellularly Glycine-gated Ion Channel Activity Extracellularly Glycine-gated Chloride Channel Activity Neurotransmitter Receptor Activity Protein-containing Complex Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	Protein Binding ATP Binding Nitrate Reductase Activity Identical Protein Binding Molybdopterin Cofactor Binding Metal Ion Binding Molybdopterin Adenylyltransferase Activity Molybdopterin Molybdotransferase Activity
	Biological Process	Startle Response Ion Transport Signal Transduction Neuropeptide Signaling Pathway Chemical Synaptic Transmission Acrosome Reaction Nervous System Development Visual Perception Adult Walking Behavior Ion Transmembrane Transport Regulation Of Membrane Potential Response To Amino Acid Nervous System Process Synaptic Transmission, Glycinergic Righting Reflex Excitatory Postsynaptic Potential Gamma-aminobutyric Acid Receptor Clustering Chloride Transmembrane Transport	Mo-molybdopterin Cofactor Biosynthetic Process Establishment Of Synaptic Specificity At Neuromuscular Junction Response To Metal Ion Molybdenum Incorporation Into Molybdenum-molybdopterin Complex Molybdopterin Cofactor Biosynthetic Process Glycine Receptor Clustering Gamma-aminobutyric Acid Receptor Clustering Postsynaptic Neurotransmitter Receptor Diffusion Trapping
Pathways		Neurotransmitter receptors and postsynaptic signal transmission Neurotransmitter receptors and postsynaptic signal transmission	Molybdenum cofactor biosynthesis
Drugs		Glycine Lindane Memantine Seletracetam Cannabidiol Medical Cannabis Nabiximols	Formic acid Imidazole Propanoic acid
Diseases
GWAS		Cognitive decline (age-related) ( 28078323) Triglyceride levels x loop diuretics use interaction ( 31806883)	Depression (quantitative trait) ( 23290196) Pneumococcal meningitis ( 31092817) Tandem gait ( 26219847) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		2 interacting genes: APP GPHN	15 interacting genes: ACADVL ARHGEF9 DYNLL1 DYNLL2 ENAH GABARAP GLRB KHDRBS1 MITD1 MTOR PFN1 PIN1 PSMA1 SPATS1 TUBA4A
Entrez ID		2743	10243
HPRD ID		11751	04893
Ensembl ID		ENSG00000109738	ENSG00000171723
Uniprot IDs		P48167	Q9NQX3
PDB IDs			1JLJ
Enriched GO Terms of Interacting Partners?
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