GPHN and GABARAP

Number of citations of the paper that reports this interaction (PubMedID 10900017)
41

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		GPHN	GABARAP
Description		gephyrin	GABA type A receptor-associated protein
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Postsynaptic Density Dendrite Postsynaptic Membrane Synaptic Membrane Anchored Component Of Synaptic Membrane Postsynaptic Specialization Postsynaptic Specialization Membrane	Golgi Membrane Autophagosome Membrane Lysosome Autophagosome Smooth Endoplasmic Reticulum Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Axoneme Actin Cytoskeleton Cytoplasmic Vesicle Cell Body Synapse Perinuclear Region Of Cytoplasm Sperm Midpiece
	Molecular Function	Protein Binding ATP Binding Nitrate Reductase Activity Identical Protein Binding Molybdopterin Cofactor Binding Metal Ion Binding Molybdopterin Adenylyltransferase Activity Molybdopterin Molybdotransferase Activity	Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding
	Biological Process	Mo-molybdopterin Cofactor Biosynthetic Process Establishment Of Synaptic Specificity At Neuromuscular Junction Response To Metal Ion Molybdenum Incorporation Into Molybdenum-molybdopterin Complex Molybdopterin Cofactor Biosynthetic Process Glycine Receptor Clustering Gamma-aminobutyric Acid Receptor Clustering Postsynaptic Neurotransmitter Receptor Diffusion Trapping	Autophagosome Assembly Microtubule Cytoskeleton Organization Autophagy Of Mitochondrion Protein Targeting Cellular Response To Nitrogen Starvation Chemical Synaptic Transmission Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Macroautophagy Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Rac Protein Signal Transduction Positive Regulation Of Protein K48-linked Ubiquitination
Pathways		Molybdenum cofactor biosynthesis	Macroautophagy TBC/RABGAPs
Drugs		Formic acid Imidazole Propanoic acid
Diseases
GWAS		Depression (quantitative trait) ( 23290196) Pneumococcal meningitis ( 31092817) Tandem gait ( 26219847) Waist circumference adjusted for body mass index ( 28552196)	Liver enzyme levels (alkaline phosphatase) ( 33972514)
Interacting Genes		15 interacting genes: ACADVL ARHGEF9 DYNLL1 DYNLL2 ENAH GABARAP GLRB KHDRBS1 MITD1 MTOR PFN1 PIN1 PSMA1 SPATS1 TUBA4A	61 interacting genes: AMBRA1 ANK2 ANK3 ATG101 ATG13 ATG3 ATG4A ATG4B ATG4C ATG4D ATG7 ATXN3 BIRC6 CUL3 DMPK DVL2 FLCN GABRG1 GABRG2 GABRG3 GJA1 GPHN HDAC5 KBTBD7 KDR LMNB1 MAPK15 MEFV MIB1 MLH1 MPC1 MYBPC2 NBR1 NEDD4 NEK9 NSF OPTN PCM1 PGS1 PKP4 PRKCZ RB1CC1 SEC62 SNX18 SQSTM1 SRPK1 SRPK2 STK3 TAX1BP1 TBC1D25 TFRC TLE5 TP53INP1 TRIM21 TRIM32 TSR2 TTN TUBB3 ULK1 ULK2 VPS28
Entrez ID		10243	11337
HPRD ID		04893	05496
Ensembl ID		ENSG00000171723	ENSG00000170296
Uniprot IDs		Q9NQX3	O95166 Q6IAW1
PDB IDs		1JLJ	1GNU 1KLV 1KM7 1KOT 3D32 3DOW 3WIM 4XC2 5DPS 6HB9 6HOG 6HOH 6HOJ 6HOK 6HYL 6HYM 6HYN 6HYO 7BRQ 7BRT 7BRU 7BV4
Enriched GO Terms of Interacting Partners?
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