NPHP3 and ASTE1

		NPHP3	ASTE1
Description		nephrocystin 3	asteroid homolog 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Cilium
	Molecular Function	Protein Binding	Nuclease Activity Protein Binding
	Biological Process	Kidney Development Heart Looping Atrial Septum Development Determination Of Left/right Symmetry Wnt Signaling Pathway Lung Development Determination Of Pancreatic Left/right Asymmetry Photoreceptor Cell Maintenance Maintenance Of Animal Organ Identity Convergent Extension Involved In Gastrulation Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Kidney Morphogenesis Determination Of Intestine Left/right Asymmetry Determination Of Stomach Left/right Asymmetry Determination Of Liver Left/right Asymmetry Ureter Development Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of Planar Cell Polarity Pathway Involved In Neural Tube Closure	Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways		Trafficking of myristoylated proteins to the cilium
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Menarche (age at onset) ( 27182965 21102462) Serum alkaline phosphatase levels ( 33547301) Subcortical volume (MOSTest) ( 32665545)	Phenylephrine infusion rate during anesthesia ( 31455332) Restless legs syndrome ( 29029846)
Interacting Genes		18 interacting genes: ANAPC13 ASTE1 ATXN1 CCDC50 CDV3 COL7A1 DDX3Y DNAJC13 DPP7 DYSF EPC1 NAA50 NPHP1 PARP14 PIK3R4 PPP2R3A RAB6B TOPBP1	2 interacting genes: NPHP3 XRCC4
Entrez ID		27031	28990
HPRD ID		06417	11038
Ensembl ID		ENSG00000113971	ENSG00000034533
Uniprot IDs		Q7Z494	D6RG30 Q2TB18
PDB IDs		5L7K
Enriched GO Terms of Interacting Partners?
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