NPHP3 and PARP14

		NPHP3	PARP14
Description		nephrocystin 3	poly(ADP-ribose) polymerase family member 14
Image
GO Annotations	Cellular Component	Extracellular Region Cytosol Cilium	Nucleus Cytoplasm Cytosol Plasma Membrane Membrane
	Molecular Function	Protein Binding	Transcription Corepressor Activity NAD+ ADP-ribosyltransferase Activity Protein Binding Enzyme Binding Protein ADP-ribosylase Activity
	Biological Process	Kidney Development Heart Looping Atrial Septum Development Determination Of Left/right Symmetry Wnt Signaling Pathway Lung Development Determination Of Pancreatic Left/right Asymmetry Photoreceptor Cell Maintenance Maintenance Of Animal Organ Identity Convergent Extension Involved In Gastrulation Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Kidney Morphogenesis Determination Of Intestine Left/right Asymmetry Determination Of Stomach Left/right Asymmetry Determination Of Liver Left/right Asymmetry Ureter Development Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of Planar Cell Polarity Pathway Involved In Neural Tube Closure	Protein ADP-ribosylation Negative Regulation Of Gene Expression Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein Innate Immune Response Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Protein Poly-ADP-ribosylation Protein Mono-ADP-ribosylation Positive Regulation Of Interleukin-4-mediated Signaling Pathway
Pathways		Trafficking of myristoylated proteins to the cilium	Nicotinamide salvaging Maturation of nucleoprotein Maturation of nucleoprotein
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Menarche (age at onset) ( 27182965 21102462) Serum alkaline phosphatase levels ( 33547301) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		18 interacting genes: ANAPC13 ASTE1 ATXN1 CCDC50 CDV3 COL7A1 DDX3Y DNAJC13 DPP7 DYSF EPC1 NAA50 NPHP1 PARP14 PIK3R4 PPP2R3A RAB6B TOPBP1	4 interacting genes: FAM162A GPI NPHP3 PARP10
Entrez ID		27031	54625
HPRD ID		06417	11421
Ensembl ID		ENSG00000113971	ENSG00000173193
Uniprot IDs		Q7Z494	Q460N5 Q8N546
PDB IDs		5L7K	3GOY 3Q6Z 3Q71 3SE2 3SMI 3SMJ 3VFQ 4ABK 4ABL 4D86 4F1L 4F1Q 4PY4 5LXP 5LYH 5NQE 5O2D 5QHT 5QHU 5QHV 5QHW 5QHX 5QHY 5QHZ 5QI0 5QI1 5QI2 5QI3 5QI4 5QI5 5QI6 5QI7 5QI8 5QI9 5QIA 5V7T 5V7W 6FYM 6FZM 6G0W 7D2C
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?