RNF11 and RNF216

Number of citations of the paper that reports this interaction (PubMedID 15231748)
99

Data Source:
BioGRID (two hybrid)

		RNF11	RNF216
Description		ring finger protein 11	ring finger protein 216
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Early Endosome Recycling Endosome Extracellular Exosome	Nucleus Nucleoplasm Cytosol Schaffer Collateral - CA1 Synapse Postsynaptic Endocytic Zone Glutamatergic Synapse
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination	Apoptotic Process Negative Regulation Of Type I Interferon Production Regulation Of Interferon-beta Production Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Defense Response To Virus By Host Protein K48-linked Ubiquitination Protein Catabolic Process, Modulating Synaptic Transmission
Pathways			Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Atrial fibrillation ( 29290336) Male-pattern baldness ( 28196072) QRS duration ( 21076409)	Parkinson's disease motor subtype (tremor to postural instability/gait difficulty score ratio) ( 33987465)
Interacting Genes		68 interacting genes: AKT1 ANKRD13A ANKRD28 APP ASCC2 AUP1 CALCOCO2 CBLB CCDC127 DCUN1D1 EPN1 EPN2 EPN3 EPS15 ERCC6 FANCL GGA1 GGA2 GGA3 HERC1 HERC2 HUWE1 IKBKG ITCH MYO6 NEDD4 NEDD4L OPTN PDCD6IP POLI PTPRC QARS1 RABGEF1 RIPK1 RNF168 RNF216 RPS27A SDCBP SMURF1 SMURF2 SNRNP70 SPRTN STAM2 STAMBP TAX1BP1 TNFAIP3 TNIP1 TOM1L2 UBA52 UBAC1 UBB UBC UBE2D1 UBE2D2 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBQLN2 UBQLN4 USP5 WWP1 WWP2 ZFYVE16 ZFYVE9 ZNF350	30 interacting genes: AGFG1 BRCA1 CAPN15 FAM168A KIR2DL4 MAPK1 MORC3 OPTN RIPK1 RNF11 SUMO2 TLR3 TLR4 TLR5 TLR9 TNFAIP3 TRAF3 UBAC1 UBASH3A UBASH3B UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2L3 UBE2L6 USP5 YOD1 ZFAND2A
Entrez ID		26994	54476
HPRD ID		09955	15550
Ensembl ID		ENSG00000123091	ENSG00000011275
Uniprot IDs		Q9Y3C5	A8K8N1 Q9NWF9
PDB IDs
Enriched GO Terms of Interacting Partners?
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