RNF11 and RNF168

Number of citations of the paper that reports this interaction (PubMedID 15231748)
99

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RNF11	RNF168
Description		ring finger protein 11	ring finger protein 168
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Early Endosome Recycling Endosome Extracellular Exosome	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytosol Protein-containing Complex Site Of Double-strand Break
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Chromatin Binding Ubiquitin-protein Transferase Activity Protein Binding Nucleosome Binding Histone Binding Ubiquitin Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination	Double-strand Break Repair Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Response To Ionizing Radiation Protein Ubiquitination Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Histone H2A Monoubiquitination Interstrand Cross-link Repair Histone H2A-K13 Ubiquitination Histone H2A-K15 Ubiquitination Isotype Switching Positive Regulation Of DNA Repair Protein K63-linked Ubiquitination Histone H2A K63-linked Ubiquitination
Pathways			SUMOylation of DNA damage response and repair proteins Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Atrial fibrillation ( 29290336) Male-pattern baldness ( 28196072) QRS duration ( 21076409)	Fat distribution (HIV) ( 21897333) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Triglyceride levels ( 32203549)
Interacting Genes		68 interacting genes: AKT1 ANKRD13A ANKRD28 APP ASCC2 AUP1 CALCOCO2 CBLB CCDC127 DCUN1D1 EPN1 EPN2 EPN3 EPS15 ERCC6 FANCL GGA1 GGA2 GGA3 HERC1 HERC2 HUWE1 IKBKG ITCH MYO6 NEDD4 NEDD4L OPTN PDCD6IP POLI PTPRC QARS1 RABGEF1 RIPK1 RNF168 RNF216 RPS27A SDCBP SMURF1 SMURF2 SNRNP70 SPRTN STAM2 STAMBP TAX1BP1 TNFAIP3 TNIP1 TOM1L2 UBA52 UBAC1 UBB UBC UBE2D1 UBE2D2 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBQLN2 UBQLN4 USP5 WWP1 WWP2 ZFYVE16 ZFYVE9 ZNF350	32 interacting genes: ALAS1 ECPAS H2AC13 H2AC18 H2AC20 H2AC4 H2AZ1 H2BC21 JMJD1C KDM1A KDM4A LAPTM5 MACROH2A1 PALB2 PARP1 RABGEF1 RNF11 RNF126 SQSTM1 SUMO2 TNFAIP3 TOP2A TRIM8 UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2G2 UBE2L3 USP7 WBP2
Entrez ID		26994	165918
HPRD ID		09955	08190
Ensembl ID		ENSG00000123091	ENSG00000163961
Uniprot IDs		Q9Y3C5	Q8IYW5
PDB IDs			3L11 4GB0 5XIS 5XIT 5XIU 5YDK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?