PAN3 and PAN2

Number of citations of the paper that reports this interaction (PubMedID 14583602)
48

Data Source:
HPRD (in vivo, in vitro)

		PAN3	PAN2
Description		poly(A) specific ribonuclease subunit PAN3	poly(A) specific ribonuclease subunit PAN2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Cytosol PAN Complex	P-body Nucleus Cytosol PAN Complex
	Molecular Function	RNA Binding Poly(A)-specific Ribonuclease Activity Protein Kinase Activity Protein Binding ATP Binding Poly(A) Binding Metal Ion Binding	3'-5'-exoribonuclease Activity Nucleic Acid Binding Poly(A)-specific Ribonuclease Activity Thiol-dependent Deubiquitinase Protein Binding Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Processing Protein Phosphorylation Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly RNA Phosphodiester Bond Hydrolysis, Exonucleolytic	Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Processing Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways		Deadenylation of mRNA	Deadenylation of mRNA
Drugs
Diseases
GWAS		Bipolar disorder ( 20351715) Body mass index ( 26426971) Granulocyte percentage of myeloid white cells ( 27863252) Hepcidin/transferrin saturation ratio ( 27846281) Mean corpuscular volume ( 32888494) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252) Pancreatic cancer ( 25086665)	Axial length ( 24144296) Height ( 34054925 25429064) Refractive error ( 32231278)
Interacting Genes		7 interacting genes: GSX1 LNX2 MTIF3 PABPC1 PAN2 SVIL TNRC6B	9 interacting genes: ATM DYNLL1 PABPC1 PAN3 RBBP8 RBCK1 RNF144B TNRC6A TRIM35
Entrez ID		255967	9924
HPRD ID		17818	15640
Ensembl ID		ENSG00000152520	ENSG00000135473
Uniprot IDs		Q58A45	Q504Q3
PDB IDs
Enriched GO Terms of Interacting Partners?
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