ITGB3BP and EFHC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ITGB3BP	EFHC1
Description		integrin subunit beta 3 binding protein	EF-hand domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Nucleus Nucleoplasm Cytoplasm Cytosol Membrane	Spindle Pole Centrosome Axoneme Neuronal Cell Body Mitotic Spindle
	Molecular Function	Protein Binding Protein C-terminus Binding	Calcium Ion Binding Protein Binding Protein C-terminus Binding Alpha-tubulin Binding
	Biological Process	Regulation Of Transcription, DNA-templated Apoptotic Process Cell Cycle Cell Adhesion Signal Transduction CENP-A Containing Nucleosome Assembly Cell Division	Mitotic Cytokinesis Mitotic Spindle Organization Cerebral Cortex Cell Migration Regulation Of Cell Division Cilium-dependent Cell Motility
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal NRIF signals cell death from the nucleus NRIF signals cell death from the nucleus Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Mean spheric corpuscular volume ( 32888494)	Atopic march ( 26542096) Clozapine-induced myocarditis in schizophrenia ( 32066683) Mean platelet volume ( 27863252) Perceived intensity of glucose ( 31005972) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) White blood cell count ( 32888494)
Interacting Genes		43 interacting genes: ACTN2 ANKRD11 APP ARFIP2 C14orf119 CCNA2 CERT1 DDX24 EFHC1 ESR1 GATAD2A GTPBP3 HSF2BP ITGB3 ITGB5 KDM1A KIAA0930 KIFC3 LRRK2 MAPK6 MAPK9 MEIS2 MEOX2 MSGN1 MTA1 NFKB1 NRDE2 NTAQ1 PBX3 PIH1D2 PIK3R3 RECQL5 RELA RXRA RXRG SNAPC5 SUOX SVIL THRA TRIML2 UBR7 USHBP1 USP20	67 interacting genes: C11orf45 C20orf85 CACNA1E CALCOCO2 CFAP161 CHCHD3 DOK7 EFHC2 EIF4ENIF1 FMR1 GADD45B GAS2L2 GOLGA2 HOMER3 IHO1 IKZF3 IMP3 ITGB3BP KCTD4 KRT15 KRT18 KRT75 LMO2 LRRC61 MAMDC2 MBD3L1 METTL27 MIIP MRNIP MTFR1L NQO2 NRIP3 NUP54 OIP5 PAX6 PBX1 PBX2 PMF1 PRR5L RCN1 REL RIMBP3 RNF125 SAPCD1 SELENOV SH3GLB2 SLAIN1 SNAI1 SORBS3 SPATA2 SYNGAP1 TCF4 TEKT1 TEX11 TLE5 TP53BP2 TRAF2 TRIP6 TRPM2 TSGA10IP TTC23L UBAP2 VBP1 WASF1 WHRN YJU2B ZBED1
Entrez ID		23421	114327
HPRD ID		09267	10583
Ensembl ID		ENSG00000142856	ENSG00000096093
Uniprot IDs		D3DQ59 Q13352	B2CKC5 Q5JVL4
PDB IDs
Enriched GO Terms of Interacting Partners?
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