EFHC1 and NQO2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EFHC1	NQO2
Description		EF-hand domain containing 1	N-ribosyldihydronicotinamide:quinone reductase 2
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Centrosome Axoneme Neuronal Cell Body Mitotic Spindle	Nucleoplasm Cytosol Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Protein C-terminus Binding Alpha-tubulin Binding	Dihydronicotinamide Riboside Quinone Reductase Activity NAD(P)H Dehydrogenase (quinone) Activity Protein Binding Zinc Ion Binding Electron Transfer Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Other Nitrogenous Compounds As Donors Chloride Ion Binding Protein Homodimerization Activity FAD Binding Melatonin Binding Resveratrol Binding
	Biological Process	Mitotic Cytokinesis Mitotic Spindle Organization Cerebral Cortex Cell Migration Regulation Of Cell Division Cilium-dependent Cell Motility	Memory Electron Transport Chain Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of ERK1 And ERK2 Cascade Quinone Catabolic Process Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways			Phase I - Functionalization of compounds
Drugs			NADH Menadione Melatonin Primaquine Resveratrol Flavin adenine dinucleotide 10-Propargyl-5,8-Dideazafolic Acid Quercetin Tretazicar (3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide 5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one Casimiroin
Diseases
GWAS		Atopic march ( 26542096) Clozapine-induced myocarditis in schizophrenia ( 32066683) Mean platelet volume ( 27863252) Perceived intensity of glucose ( 31005972) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) White blood cell count ( 32888494)	Blood protein levels ( 30072576 29875488) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		67 interacting genes: C11orf45 C20orf85 CACNA1E CALCOCO2 CFAP161 CHCHD3 DOK7 EFHC2 EIF4ENIF1 FMR1 GADD45B GAS2L2 GOLGA2 HOMER3 IHO1 IKZF3 IMP3 ITGB3BP KCTD4 KRT15 KRT18 KRT75 LMO2 LRRC61 MAMDC2 MBD3L1 METTL27 MIIP MRNIP MTFR1L NQO2 NRIP3 NUP54 OIP5 PAX6 PBX1 PBX2 PMF1 PRR5L RCN1 REL RIMBP3 RNF125 SAPCD1 SELENOV SH3GLB2 SLAIN1 SNAI1 SORBS3 SPATA2 SYNGAP1 TCF4 TEKT1 TEX11 TLE5 TP53BP2 TRAF2 TRIP6 TRPM2 TSGA10IP TTC23L UBAP2 VBP1 WASF1 WHRN YJU2B ZBED1	10 interacting genes: CSF3 DDIT4L DGCR6 DRD2 EFHC1 GORASP2 IL32 LRRC7 MTCH1 SPG21
Entrez ID		114327	4835
HPRD ID		10583	01190
Ensembl ID		ENSG00000096093	ENSG00000124588
Uniprot IDs		B2CKC5 Q5JVL4	B3KPX6 P16083 Q5TD07
PDB IDs			1QR2 1SG0 1XI2 1ZX1 2BZS 2QMY 2QMZ 2QR2 2QWX 2QX4 2QX6 2QX8 2QX9 3FW1 3G5M 3GAM 3NFR 3NHF 3NHJ 3NHK 3NHL 3NHP 3NHR 3NHS 3NHU 3NHW 3NHY 3O2N 3O73 3OVM 3OWH 3OWX 3OX1 3OX2 3OX3 3TE7 3TEM 3TZB 3UXE 3UXH 4FGJ 4FGK 4FGL 4GQI 4GR9 4QOD 4QOE 4QOF 4QOG 4QOH 4QOI 4QOJ 4U7F 4U7G 4U7H 4XDG 4XDH 4ZVK 4ZVL 4ZVM 4ZVN 5BUC 5LBT 5LBU 5LBW 5LBY 5LBZ
Enriched GO Terms of Interacting Partners?
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