MAP2K4 and MAP3K12

  • Number of citations of the paper that reports this interaction (PubMedID 10187804)
  • 34
  • Data Source:
  • HPRD (in vitro)

MAP2K4

MAP3K12

Description mitogen-activated protein kinase kinase 4 mitogen-activated protein kinase kinase kinase 12
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Asthma ( 32296059)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Estimated glomerular filtration rate ( 31152163)
  • Response to amphetamines ( 22952603)
  • Serum alkaline phosphatase levels ( 33339817)
  • Body mass index ( 28892062)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 44 interacting genes: AKT1 ALDOB APP ARRB1 ARRB2 CFLAR CYLC2 DUSP22 EFNA4 FBP2 FLNA FLNC GEMIN5 ITCH JUN LRRK2 MAP2K6 MAP3K1 MAP3K10 MAP3K11 MAP3K12 MAP3K14 MAP3K2 MAP3K20 MAP3K3 MAP3K4 MAP3K5 MAP3K7 MAP3K8 MAP4K2 MAPK1 MAPK10 MAPK12 MAPK14 MAPK7 MAPK8 MAPK8IP3 MAPK9 NBR1 RBBP8 SPAG9 STX17 TRIB1 UBC 16 interacting genes: EGFR FRA10AC1 FTL MAP2K4 MAP2K7 MAP3K11 MAPK6 MAPK8IP1 MAPK8IP2 MBIP MTDH RGS1 RPL18A SH3RF1 TGM2 TSC22D1
Entrez ID 6416 7786
HPRD ID 03213 02709
Ensembl ID ENSG00000065559 ENSG00000139625
Uniprot IDs P45985 A0A024RAY5 Q12852
PDB IDs 3ALN 3ALO 3VUT 5CEN 5CEO 5CEP 5CEQ 5VO1 5VO2
Enriched GO Terms of Interacting Partners?
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