EZH2 and SMYD3

  • Number of citations of the paper that reports this interaction (PubMedID 22659877)
  • 84
  • Data Source:
  • BioGRID (unspecified method)

EZH2

SMYD3

Description enhancer of zeste 2 polycomb repressive complex 2 subunit SET and MYND domain containing 3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronotype ( 30696823)
  • Colorectal or endometrial cancer ( 26621817)
  • Crohn's disease ( 28067908)
  • Familial squamous cell lung carcinoma ( 29924316)
  • Height ( 25282103 31562340)
  • Inflammatory bowel disease ( 28067908)
  • Mean reticulocyte volume ( 32888494)
  • Mean spheric corpuscular volume ( 32888494)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 25673412)
  • Bipolar disorder ( 31043756)
  • Blood metabolite levels ( 26401656)
  • Coffee consumption ( 31046077)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Fractional exhaled nitric oxide (childhood) ( 24315451)
  • Gut microbiota relative abundance (Bifidobacterium) ( 33208821)
  • Malaria ( 31844061)
  • Obesity-related traits ( 23251661)
  • Post bronchodilator FEV1 ( 26634245)
  • PR interval ( 32439900)
  • Renal underexcretion gout ( 32238385)
  • Response to serotonin reuptake inhibitors in non-psychotic unipolar depression ( 26348319)
  • Systemic lupus erythematosus ( 29848360)
  • Upper eyelid sagging severity ( 24869959)
Interacting Genes 77 interacting genes: AKT1 AR ATP1A1 ATP1B1 ATRX BCL11A BRCA1 C7orf25 CCDC85B CDK2 CDK6 CDKN2B-AS1 CEP63 CRY2 DELEC1 DNAJB11 DNMT1 DNMT3A DNMT3B E2F6 EED EHMT1 EPC2 FBXW7 GADD45G GTF3C1 H1-1 H3-4 HDAC1 HOTAIR JAK2 KAT2B KLHDC2 KRTAP10-9 LATS2 LINC00511 MAP3K20 MAP3K7 MAPK8IP2 MAPKAPK3 MED1 MELK MUC1 MYCN NINL PFDN1 PHB2 PHF1 PIN4 PJA1 POLA2 PRDM14 PRMT5 PSMB6 RASA1 RBL2 RELA RELB RIN3 RPN2 RPS6KA5 SIRT1 SMN1 SMS SMYD3 SUV39H1 SUZ12 TAF1D TK1 TNFSF11 TRIM55 TRIM63 USP1 VAV1 WDR61 WSB2 ZMYND11 22 interacting genes: APP CAMK2B CSTF2T CYP39A1 EED EZH2 H3-4 H3-5 HELZ HSP90AA1 MKRN3 NDUFAB1 NFYB NUP54 PBX2 PKN1 POLR2K SCCPDH SHC3 TRIT1 VANGL1 ZNF557
Entrez ID 2146 64754
HPRD ID 03342 12297
Ensembl ID ENSG00000106462 ENSG00000185420
Uniprot IDs A0A090N8E9 Q15910 S4S3R8 B3KN46 Q9H7B4
PDB IDs 2C6V 4MI0 4MI5 5GSA 5H14 5H15 5H17 5H19 5H24 5H25 5HYN 5IJ7 5IJ8 5LS6 5U5T 5U62 5WG6 5WUK 6C23 6C24 6P5L 6U4Y 6WKR 7AT8 3MEK 3OXF 3OXG 3OXL 3PDN 3QWP 3RU0 5CCL 5CCM 5EX0 5EX3 5HI7 5HQ8 5V37 5XXD 5XXG 5XXJ 5YJO 6IJL 6O9O 6P6G 6P6K 6P7Z 6PAF 6YUH 7BJ1
Enriched GO Terms of Interacting Partners?
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